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CAS 115966-23-9

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Urodilatin

Description:
Urodilatin is a peptide that is derived from the prohormone pro-atrial natriuretic peptide (pro-ANP) and is primarily involved in the regulation of renal function and fluid balance. It is characterized by its role as a natriuretic agent, promoting the excretion of sodium and water, which helps to reduce blood volume and lower blood pressure. Urodilatin is produced in the kidneys and acts on the renal tubules, enhancing diuresis and natriuresis. Its structure consists of a sequence of amino acids that confer its biological activity, and it is known to interact with specific receptors in the body, leading to vasodilation and increased glomerular filtration rate. Urodilatin's therapeutic potential is being explored in conditions such as heart failure and hypertension, where fluid overload is a concern. Overall, its unique properties make it an important molecule in cardiovascular and renal physiology.
Formula:C145H234N52O44S3
InChI:InChI=1/C145H234N52O44S3/c1-11-72(6)112-137(238)171-60-106(208)172-73(7)113(214)177-86(40-41-103(146)205)122(223)190-95(63-198)116(217)170-61-108(210)175-88(51-70(2)3)114(215)169-62-109(211)176-100(133(234)187-92(56-104(147)206)127(228)193-97(65-200)130(231)186-91(54-77-27-16-13-17-28-77)126(227)180-82(31-20-45-163-142(153)154)119(220)189-94(139(240)241)55-78-36-38-79(204)39-37-78)68-243-244-69-101(134(235)185-90(53-76-25-14-12-15-26-76)115(216)168-58-105(207)167-59-107(209)174-80(29-18-43-161-140(149)150)117(218)182-87(42-50-242-10)123(224)188-93(57-110(212)213)128(229)181-85(124(225)196-112)34-23-48-166-145(159)160)195-132(233)99(67-202)194-131(232)98(66-201)192-120(221)83(32-21-46-164-143(155)156)178-118(219)81(30-19-44-162-141(151)152)179-125(226)89(52-71(4)5)184-129(230)96(64-199)191-121(222)84(33-22-47-165-144(157)158)183-135(236)102-35-24-49-197(102)138(239)74(8)173-136(237)111(148)75(9)203/h12-17,25-28,36-39,70-75,80-102,111-112,198-204H,11,18-24,29-35,40-69,148H2,1-10H3,(H2,146,205)(H2,147,206)(H,167,207)(H,168,216)(H,169,215)(H,170,217)(H,171,238)(H,172,208)(H,173,237)(H,174,209)(H,175,210)(H,176,211)(H,177,214)(H,178,219)(H,179,226)(H,180,227)(H,181,229)(H,182,218)(H,183,236)(H,184,230)(H,185,235)(H,186,231)(H,187,234)(H,188,224)(H,189,220)(H,190,223)(H,191,222)(H,192,221)(H,193,228)(H,194,232)(H,195,233)(H,196,225)(H,212,213)(H,240,241)(H4,149,150,161)(H4,151,152,162)(H4,153,154,163)(H4,155,156,164)(H4,157,158,165)(H4,159,160,166)/t72-,73-,74-,75+,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,111-,112-/m0/s1
Synonyms:
  • Anp 95-126
  • H-Thr-Ala-Pro-Arg-Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr-OH (Disulfide bond)
  • Proatrial natriuretic peptide (95-126)
  • Thr-Ala-Pro-Arg-Atrial Natriuretic Factor (1-28) (human)
  • Urodilatin
  • Urodilatin (CDD/ANP-95-126)
  • THR-ALA-PRO-ARG-ATRIAL NATRIURETIC PEPTIDE
  • URODILATIN CCC/ANP, 95-126
  • Thr-Ala-Pro-Arg-Atrial Natriuretic Peptide, Urodilatin, human
  • H-THR-ALA-PRO-ARG-SER-LEU-ARG-ARG-SER-SER-CYS-PHE-GLY-GLY-ARG-MET-ASP-ARG-ILE-GLY-ALA-GLN-SER-GLY-LEU-GLY-CYS-ASN-SER-PHE-ARG-TYR-OH (DISULFIDE BRIDGE: 11-27)
  • See more synonyms
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Found 4 products.
  • Thr-Ala-Pro-Arg-Atrial Natriuretic Factor (1-28) (human, bovine, porcine)
    Bachem
    + Info

    Thr-Ala-Pro-Arg-Atrial Natriuretic Factor (1-28) (human, bovine, porcine)

    CAS:
    Urodilatin, a 32 amino acid peptide, has originally been isolated from human urine. It belongs to the family of natriuretic-vasorelaxant peptides earlier found in heart atria. Cedidi et al. showed that urodilatin infusion may represent a concept for the treatment of therapy-resistant acute renal failure after liver transplantation. The use of ularitide is protected by patents. It is sold by Bachem for research purposes only, by expressed permission of Pharis Biotec GmbH, Hannover, Germany (www.pharis-biotec.com).
    Formula:C145H234N52O44S3
    Purity:≥ 95%
    Color and Shape:White Powder
    Molecular weight:3505.98

    Ref: 01-4030382

    1mg
    481.00€
    0.5mg
    267.00€
  • Urodilatin
    Indagoo
    + Info

    Urodilatin

    CAS:
    Formula:C145H234N52O44S3
    Purity:95%
    Molecular weight:3505.9265

    Ref: IN-DA000H8N

    1mg
    133.00€
    5mg
    516.00€
    25mg
    To inquire
    100mg
    To inquire
  • CymitQuimica logo
    Targetmol
    + Info

    Urodilatin

    CAS:
    <p>Urodilatin, an analogue of ANF-(99-126), serves as a diuretic-natriuretic regulatory peptide with applications in the study of acute renal failure, congestive</p>
    Color and Shape:Solid

    Ref: TM-T80891

  • Thr-Ala-Pro-Arg-Atrial Natriuretic Factor (1-28) (human, bovine, porcine) trifluoroacetate salt
    Biosynth
    + Info

    Thr-Ala-Pro-Arg-Atrial Natriuretic Factor (1-28) (human, bovine, porcine) trifluoroacetate salt

    CAS:
    <p>Thr-Ala-Pro-Arg-Atrial Natriuretic Factor (1-28) (human, bovine, porcine) trifluoroacetate salt is a peptide hormone that regulates blood pressure by causing the kidneys to excrete sodium and water. It is used as a model system for studying the physiological effects of urodilatin and has been shown to inhibit the cyclase enzyme. Thr-Ala-Pro-Arg-Atrial Natriuretic Factor (1-28) (human, bovine, porcine) trifluoroacetate salt may also have an antihypertensive effect through its ability to reduce levels of natriuretic peptides in plasma. This drug is also being investigated as a possible treatment for congestive heart failure. The small molecular weight makes it suitable for use as a natriuretic or antihypertensive drug with minimal side effects.</p>
    Formula:C145H234N52O44S3
    Purity:Min. 95%
    Molecular weight:3,505.93 g/mol

    Ref: 3D-FT108857

    1mg
    860.00€
    2mg
    1,088.00€
    5mg
    2,286.00€