CAS 1160861-53-9

2-(Di-t-butylphosphino)-3,6-dimethoxy-2'-4'-6'-tri-i-propyl-1,1'-biphenyl

Description:

2-(Di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl is a complex organophosphorus compound characterized by its unique structural features, including a biphenyl backbone and multiple substituents. The presence of di-t-butylphosphino groups imparts significant steric bulk, which can influence its reactivity and coordination properties in various chemical environments. The methoxy groups contribute to the compound's solubility and electronic properties, potentially enhancing its role as a ligand in coordination chemistry. The tri-isopropyl substituents further increase steric hindrance, which may affect the compound's interactions with metal centers in catalysis. This compound is likely to exhibit interesting properties in organometallic chemistry, particularly in catalysis and ligand design, due to its ability to stabilize metal complexes. Additionally, its structural complexity suggests potential applications in materials science and organic synthesis, where tailored reactivity and selectivity are essential. Overall, this compound exemplifies the intricate interplay between sterics and electronics in organophosphorus chemistry.

Formula: C31H49O2P

InChI: InChI=1S/C31H49O2P/c1-19(2)22-17-23(20(3)4)27(24(18-22)21(5)6)28-25(32-13)15-16-26(33-14)29(28)34(30(7,8)9)31(10,11)12/h15-21H,1-14H3

InChI key: REWLCYPYZCHYSS-UHFFFAOYSA-N

SMILES: CC(C)C1=CC(=C(C(=C1)C(C)C)C2=C(C=CC(=C2P(C(C)(C)C)C(C)(C)C)OC)OC)C(C)C

Synonyms:

• t-butylBrettPhos

Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine

CAS: 1160861-53-9

Formula: C₃₁H₄₉O₂P

Purity: >98.0%(T)(qNMR)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 484.70

Ref: 3B-D5663

2-(Di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% t-BuBrettPhos

CAS: 1160861-53-9

2-(Di-t-butylphosphino)-3,6-dimethoxy-2',4',6'-tri-i-propyl-1,1'-biphenyl, min. 98% t-BuBrettPhos

Formula: C₃₁H₄₉O₂P

Purity: min. 98%

Color and Shape: white xtl.

Molecular weight: 484.69

Ref: 08-15-1164

Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxybiphenyl-2-yl)phosphine

CAS: 1160861-53-9

Formula: C₃₁H₄₉O₂P

Purity: 98%

Color and Shape: Solid

Molecular weight: 484.6933

Ref: IN-DA000BKH

2-(Di-tert-butylphosphino)-2',4',6'- triisopropyl-3,6-dimethoxy-1,1'-biphenyl

CAS: 1160861-53-9

2-(Di-tert-butylphosphino)-2',4',6'-triisopropyl-3,6-dimethoxy-1,1'-biphenyl is a nucleophilic compound that can be used in amination reactions. It has been used to synthesize fluorinated compounds by reacting with various halides under palladium catalysis. This reaction is an efficient method for the synthesis of 5-membered heteroaryl compounds and pyrazole rings. 2-(Di-tert-butylphosphino)-2',4',6'-triisopropyl-3,6-dimethoxy-1,1'-biphenyl has also been shown to inhibit the growth of carcinoma cell lines and profiles in aminoimidazoles.

Formula: C₃₁H₄₉O₂P

Purity: Min. 97 Area-%

Color and Shape: White Off-White Powder

Molecular weight: 484.69 g/mol

Ref: 3D-FD44709

t-BuBrettPhos

CAS: 1160861-53-9

Di-tert-butyl(2',4',6'-triisopropyl-3,6-dimethoxy-[1,1'-biphenyl]-2-yl)phosphine

Formula: C₃₁H₄₉O₂P

Purity: 98%

Molecular weight: 484.69

Ref: IN-DG225201

tert-ButylBrettPhos

Controlled Product

CAS: 1160861-53-9

Applications tert-ButylBrettPhos is a ligand commonly found on palladium catalysts used in the regioselective 2-amination of polychloropyrimidines.
References Smith, S.M., Buchwald, S.L., Org. Lett., 9, 2180-2183 (2016)

Formula: C₃₁H₄₉O₂P

Color and Shape: Neat

Molecular weight: 484.69

Ref: TR-B694080