CAS 1163135-95-2

5,6-trans-Bimatoprost

Description:

5,6-trans-Bimatoprost, identified by its CAS number 1163135-95-2, is a synthetic prostaglandin analog primarily used in ophthalmology for the treatment of glaucoma and ocular hypertension. This compound is characterized by its ability to increase the outflow of aqueous humor, thereby reducing intraocular pressure. Structurally, it features a long hydrocarbon chain with specific functional groups that contribute to its biological activity. The "trans" configuration at the 5 and 6 positions indicates the geometric arrangement of the molecule, which is crucial for its interaction with the prostaglandin receptors. Bimatoprost is known for its potency and selectivity, making it effective in promoting eyelash growth as well. It is typically administered as an eye drop solution and is well-tolerated, although some users may experience side effects such as eye irritation or changes in eyelash pigmentation. Overall, 5,6-trans-Bimatoprost exemplifies the application of synthetic compounds in therapeutic settings, particularly in managing ocular conditions.

Bimatoprost Related Compound A ((E)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(S,E)-3-hydroxy-5-phenylpent-1-en-1-yl]cyclopentyl]-N-ethylhept-5-enamide)

CAS: 1163135-95-2

Aromatic cyclic amides (including cyclic carbamates) and their derivatives; salts thereof

Formula: C₂₅H₃₇NO₄

Color and Shape: Liquid

Molecular weight: 415.27226

Ref: 45-1071359

Bimatoprost USP Related Compound A (5-trans Bimatoprost)

CAS: 1163135-95-2

Formula: C₂₅H₃₇NO₄

Color and Shape: White Semi-Solid To Solid (Low M P )

Molecular weight: 415.57

Ref: 4Z-B-246

Bimatoprost USP Related Compound A-d5 (5-trans Bimatoprost-d5)

CAS: 1163135-95-2

Formula: C₂₅H₃₂D₅NO₄

Molecular weight: 420.60

Ref: 4Z-B-2423

Bimatoprost USP Related Compound A

CAS: 1163135-95-2

Formula: C₂₅H₃₇NO₄

Molecular weight: 415.57

Ref: ST-EA-CP-B40002

(5E)-Bimatoprost

CAS: 1163135-95-2

Applications The trans-isomer used in the improved process for the production and purification of Bimatoprost (B386800).

Formula: C₂₅H₃₇NO₄

Color and Shape: Neat

Molecular weight: 415.56

Ref: TR-B386810

(5E)-Bimatoprost-d5

Controlled Product

CAS: 1163135-95-2

Formula: C₂₅D₅H₃₂NO₄

Color and Shape: Neat

Molecular weight: 420.596

Ref: TR-B386812

5-trans-Bimatoprost

CAS: 1163135-95-2

5-trans-Bimatoprost is a synthetic prostaglandin analog that inhibits the activity of cyclooxygenase, leading to the production of vasodilatory and anti-inflammatory prostanoids. It is used in ophthalmology as a glaucoma treatment. 5-trans-Bimatoprost is also used for the treatment of glaucoma, which can be caused by increased intraocular pressure from several factors such as age and diabetes mellitus. 5-trans-Bimatoprost also has hypotensive effects and can be used for patients with high blood pressure or heart failure. 5-trans-Bimatoprost was first synthesized in 1974 and has been shown to have a structural similarity to anandamide, which is an endocannabinoid that binds to CB1 receptors in the brain. This chemical structure may explain why 5-trans-Bimatoprost has similar biological effects as anandamide

Formula: C₂₅H₃₇NO₄

Purity: Min. 95 Area-%

Color and Shape: Clear Liquid

Molecular weight: 415.57 g/mol

Ref: 3D-FB18598