CAS 1164153-22-3

Formula: C27H27N5O5

InChI: InChI=1S/C27H27N5O5/c1-17-7-5-9-19(11-17)30-27(34)31-21-15-28-32(16-21)22-10-6-8-18(12-22)26(33)29-20-13-23(35-2)25(37-4)24(14-20)36-3/h5-16H,1-4H3,(H,29,33)(H2,30,31,34)

InChI key: MTFAYLZZDJGFGV-UHFFFAOYSA-N

SMILES: CC1=CC(=CC=C1)NC(=O)NC2=CN(N=C2)C3=CC=CC(=C3)C(=O)NC4=CC(=C(C(=C4)OC)OC)OC

Sr 3576

CAS: 1164153-22-3

Sr 3576

Formula: C₂₇H₂₇N₅O₅

Molecular weight: 501.53378

Ref: 54-BISN0280

SR 3576

CAS: 1164153-22-3

Formula: C₂₇H₂₇N₅O₅

Purity: 98%

Molecular weight: 501.5338

Ref: IN-DA01ENFE

SR 3576

Controlled Product

CAS: 1164153-22-3

Formula: C₂₇H₂₇N₅O₅

Color and Shape: Neat

Molecular weight: 501.534

Ref: TR-S684518

JNK3 Inhibitor XII, SR-3576

CAS: 1164153-22-3

JNK3 Inhibitor XII is a small molecule inhibitor of c-Jun N-terminal kinase 3 (JNK3) and has been shown to suppress the proliferation of tumor cells in vitro. JNK3 Inhibitor XII inhibits cell proliferation by activating endogenous retroviruses, which are DNA sequences that are present in all human cells. The retroviral gene products can inhibit cell division and induce apoptosis. In addition, JNK3 Inhibitor XII has been shown to dampen the activation of FoxM1, a transcription factor that stimulates cancer cell growth. This compound also activates endogenous sequences that are expressed across populations and may be involved in regulating pluripotent stem cells or heart disease.

Formula: C₂₇H₂₇N₅O₅

Purity: Min. 95%

Molecular weight: 501.53 g/mol

Ref: 3D-PWB15322

SR 3576

CAS: 1164153-22-3

SR 3576 is an aminopyrazole-type JNK inhibitor with an IC₅₀ of 7 nM for JNK3 and a selectivity of more than 2,800-fold towards p38; it can be used in studies relating to JNK signalling.

Formula: C₂₇H₂₇N₅O₅

Purity: 99.83%

Color and Shape: Solid

Molecular weight: 501.53

Ref: TM-T23392