CAS 116430-60-5

D-Phenylalanyl-cysteinyl-tyrosyl-D-tryptophyl-lysyl-valyl-cysteinyl-tryptophylamide cyclic (2-7)-disulfide acetate

Description:

D-Phenylalanyl-cysteinyl-tyrosyl-D-tryptophyl-lysyl-valyl-cysteinyl-tryptophylamide cyclic (2-7)-disulfide acetate, with CAS number 116430-60-5, is a cyclic peptide characterized by its unique sequence of amino acids and the presence of disulfide bonds, which contribute to its structural stability and biological activity. The cyclic nature of this compound allows for a specific three-dimensional conformation, which is crucial for its interaction with biological targets, potentially influencing various physiological processes. The inclusion of cysteine residues facilitates the formation of disulfide bridges, enhancing the rigidity of the molecule. This compound may exhibit properties such as antimicrobial activity, neuroprotective effects, or modulation of neurotransmitter systems, depending on its specific interactions within biological systems. Additionally, the acetate group may influence solubility and bioavailability. Overall, the structural features of this cyclic peptide suggest potential applications in pharmaceuticals, particularly in the development of therapeutic agents targeting specific biological pathways.

Formula: C₅₉H₇₄N₁₂O₁₁S₂

Synonyms:

• Vapreotide acetate
• Bmy-41606
• Rc-160
• Sanvar
• Octastatin
• D-Phenylalanyl-cysteinyl-tyrosyl-D-tryptophyl-lysyl-valyl-cysteinyl-tryptophylamide cyclic (2-7)-disulfide acetate
• D-Phenylalanyl-cysteinyl-tyrosyl-D-tryptophyl-lysyl-valyl-cy...

Vapreotide Acetate

CAS: 116430-60-5

Formula: C₅₇H₇₀N₁₂O₉S₂

Purity: 95%~99%

Color and Shape: White to Off-white Powder

Molecular weight: 1131.37

Ref: BP-BPPG069

Vapreotide Acetate

Controlled Product

CAS: 116430-60-5

Stability Hygroscopic
Applications Vapreotide is a synthetic somatostatin (S676750) analog predominately used for the treatment of acute variceal bleeding.
References Fortune, B.E., et al.: Expert. Opin. Pharmacother., 10, 14 (2009); Paul, C., et al.: Eng. J. Med., 344, 23 (2001);

Formula: C₅₉H₇₄N₁₂O₁₁S₂

Color and Shape: Neat

Molecular weight: 1191.42

Ref: TR-V097800

Vapreotide acetate

CAS: 116430-60-5

Vapreotide acetate is an anti-cancer compound that is derived from a peptide hormone. It inhibits the growth of cancer cells by binding to the neurokinin-1 receptor, which may be involved in the regulation of cell proliferation and apoptosis. Vapreotide acetate has been shown to inhibit IGF-I (insulin-like growth factor 1) and somatostatin release in vitro. The molecular docking analysis of vapreotide acetate with the neurokinin-1 receptor has been performed using a computer program. The potency of vapreotide acetate was found to be comparable to other analogs such as octreotide acetate and lanreotide acetate in inhibiting cell proliferation in human osteosarcoma cell lines. Vapreotide acetate has also been shown to have anti-inflammatory properties due to its ability to inhibit plasma mass spectrometry for cytokines such as IL-6, TNFα, IL-8,

Formula: C₅₇H₇₀N₁₂O₉S₂•C₂H₄O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 1,191.43 g/mol

Ref: 3D-FV73145