CAS 116611-64-4

Fmoc-His-OH

Description:

Fmoc-His-OH, or Fmoc-histidine, is a protected form of the amino acid histidine, commonly used in peptide synthesis. The "Fmoc" (9-fluorenylmethoxycarbonyl) group serves as a protective group for the amino functionality of histidine, allowing for selective reactions during the synthesis of peptides. This compound is characterized by its ability to undergo deprotection under mild basic conditions, which is advantageous in synthetic chemistry. Fmoc-His-OH is typically a white to off-white solid and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its structure includes an imidazole side chain, which can participate in various interactions, making it valuable in the design of biologically active peptides. The presence of the Fmoc group also facilitates purification and characterization of the resulting peptides. Overall, Fmoc-His-OH is an essential building block in the field of peptide chemistry and biochemistry.

Formula: C₂₁H₁₉N₃O₄

InChI: InChI=1S/C21H19N3O4/c25-20(26)19(9-13-10-22-12-23-13)24-21(27)28-11-18-16-7-3-1-5-14(16)15-6-2-4-8-17(15)18/h1-8,10,12,18-19H,9,11H2,(H,22,23)(H,24,27)(H,25,26)/t19-/m0/s1

InChI key: SIRPVCUJLVXZPW-IBGZPJMESA-N

SMILES: C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)N[C@@H](CC4=CN=CN4)C(=O)O

Synonyms:

• N-α-Fmoc-L-histidine
• Fmoc-L-histidine

Fmoc-His-OH

CAS: 116611-64-4

Bachem ID: 4013285.

Formula: C₂₁H₁₉N₃O₄

Purity: 99.8%

Color and Shape: White

Molecular weight: 377.4

Ref: 01-4013285

Fmoc-His-OH

CAS: 116611-64-4

Fmoc-His-OH

Formula: C₂₁H₁₉N₃O₄

Purity: 99.5%

Molecular weight: 377.39

Ref: 54-BUP19530

N-Fmoc-L-Histidine

CAS: 116611-64-4

N-Fmoc-L-Histidine

Formula: C₂₁H₁₉N₃O₄

Purity: >98%

Color and Shape: Solid

Molecular weight: 377.39

Ref: 54-OR1014374

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid

CAS: 116611-64-4

Formula: C₂₁H₁₉N₃O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 377.3933

Ref: IN-DA000CVI

Fmoc-His-OH

CAS: 116611-64-4

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(1H-imidazol-4-yl)propanoic acid

Formula: C₂₁H₁₉N₃O₄

Purity: 98%

Molecular weight: 377.39

Ref: IN-DG30378

Semaglutide Impurity 26

CAS: 116611-64-4

Formula: C₂₁H₁₉N₃O₄

Molecular weight: 377.40

Ref: 4Z-PS-189041

Fmoc-HIS-OH

CAS: 116611-64-4

Fmoc-His-OH (FMOC-L-Histidine) is a histidine derivative and a common material for peptide synthesis.

Formula: C₂₁H₁₉N₃O₄

Purity: 98.38% - 99.82%

Color and Shape: White Solid

Molecular weight: 377.3933

Ref: TM-T66645

N-alpha-Fmoc-L-histidine

CAS: 116611-64-4

N-alpha-Fmoc-L-histidine is a diagnostic agent that can be used to diagnose and treat prostate cancer. It has been shown to be an effective chemotherapeutic agent against prostate cancer, with a mechanism of action that is dependent on the microenvironment of the tumor tissue. N-alpha-Fmoc-L-histidine can be conjugated to other agents like doxorubicin, which will increase its therapeutic potential. The conjugates are taken up by prostate carcinoma cells via receptor mediated endocytosis and then released inside the cell, where they induce apoptosis. This process is independent of p53 status and does not require metabolic activation.

Formula: C₂₁H₁₉N₃O₄

Purity: Min. 95%

Molecular weight: 377.39 g/mol

Ref: 3D-FF48584

Fmoc-His-OH

CAS: 116611-64-4

Formula: C₂₁H₁₉N₃O₄

Molecular weight: 377.4

Ref: BE-RMCP512040

Fmoc-L-Histidine

CAS: 116611-64-4

Formula: C₂₁H₁₉N₃O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 377.138

Ref: 10-F222016

FMOC-L-Histidine extrapure, 98%

CAS: 116611-64-4

Formula: C₂₁H₁₉N₃O₄

Purity: min. 98%

Color and Shape: White to off white, Crystalline powder

Molecular weight: 377.40

Ref: SR-17849

N-α-Fmoc-L-histidine-3-15N

Controlled Product

CAS: 116611-64-4

Formula: C₂₁H₁₉₁₅NN₂O₄

Color and Shape: Neat

Molecular weight: 378.387

Ref: TR-F633002

Semaglutide Impurity 38

CAS: 116611-64-4

Formula: C₂₁H₁₉N₃O₄

Molecular weight: 377.4

Ref: ST-EA-CP-S78052