CAS 117106-20-4

O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine

Description:

O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine, commonly referred to by its CAS number 117106-20-4, is a synthetic compound primarily used in peptide synthesis and as a protecting group in organic chemistry. This molecule features a threonine amino acid backbone, which is modified with a tert-butyl group (1,1-dimethylethyl) and a fluorenylmethoxycarbonyl (Fmoc) protecting group. The Fmoc group is widely utilized for its stability under basic conditions and ease of removal under acidic conditions, making it advantageous in solid-phase peptide synthesis. The presence of the methyl group on the nitrogen atom contributes to the steric hindrance, influencing the compound's reactivity and solubility. This compound is typically characterized by its solid-state properties, including melting point and solubility in organic solvents. Its unique structure allows for specific interactions in biochemical applications, particularly in the synthesis of peptides and proteins, facilitating the study of biological processes and the development of pharmaceuticals.

Formula: C₂₄H₂₉NO₅

InChI: InChI=1S/C24H29NO5/c1-15(30-24(2,3)4)21(22(26)27)25(5)23(28)29-14-20-18-12-8-6-10-16(18)17-11-7-9-13-19(17)20/h6-13,15,20-21H,14H2,1-5H3,(H,26,27)/t15-,21+/m1/s1

InChI key: InChIKey=VIUVLZHFMIFLHU-VFNWGFHPSA-N

SMILES: C(OC(N([C@@H]([C@H](OC(C)(C)C)C)C(O)=O)C)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• <span class="text-smallcaps">L</span>-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• N-Fmoc-N-Methyl-O-Tert-Butyl-L-Threonine
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-<span class="text-smallcaps">L</span>-threonine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine
• L-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-L-threonine

N-Fmoc-O-tert-butyl-N-methyl-L-threonine, 99%

CAS: 117106-20-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₄H₂₉NO₅

Purity: 99%

Molecular weight: 411.50

Ref: 02-H63170

Fmoc-N-Me-Thr(tBu)-OH

CAS: 117106-20-4

Bachem ID: 4029146.

Formula: C₂₄H₂₉NO₅

Purity: 98.7%

Color and Shape: White

Molecular weight: 411.5

Ref: 01-4029146

L-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-methyl-

CAS: 117106-20-4

Formula: C₂₄H₂₉NO₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 411.4908

Ref: IN-DA000DQR

Fmoc-N-Me-Thr(tBu)-OH

CAS: 117106-20-4

Ref: 7W-GM6153

Fmoc-N-Me-Thr(tBu)-OH

CAS: 117106-20-4

Fmoc-N-Me-Thr(tBu)-OH

Purity: 95%

Color and Shape: Solid

Molecular weight: 411.49g/mol

Ref: 54-OR36416

Fmoc-N-Me-Thr(tBu)-OH

CAS: 117106-20-4

M03390 - Fmoc-N-Me-Thr(tBu)-OH

Formula: C₂₄H₂₉NO₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 411.498

Ref: 10-M03390