CymitQuimica logo

CAS 1173-26-8

:

Corticosterone acetate

Description:
Corticosterone acetate is a synthetic derivative of corticosterone, a steroid hormone produced by the adrenal cortex. It is classified as a glucocorticoid and is primarily used in research and therapeutic applications due to its anti-inflammatory and immunosuppressive properties. The substance appears as a white to off-white crystalline powder and is soluble in organic solvents such as ethanol and methanol, but has limited solubility in water. Its molecular structure includes a steroid backbone with an acetate group, which enhances its lipophilicity and bioavailability. Corticosterone acetate is often utilized in studies related to stress response, metabolism, and endocrine function. In laboratory settings, it may be administered to animal models to investigate its physiological effects or to develop treatments for conditions like autoimmune diseases and allergies. As with other glucocorticoids, caution is advised regarding its use, as it can lead to side effects such as hormonal imbalances and metabolic disturbances when used improperly.
Formula:C23H32O5
InChI:InChI=1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1
InChI key:InChIKey=WKQCPUMQBMFPLC-ZWFCQKKLSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@@H](C(COC(C)=O)=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]
Synonyms:
  • (11Beta)-11-Hydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
  • (11β)-21-(Acetyloxy)-11-hydroxypregn-4-ene-3,20-dione
  • 11-Hydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
  • Cort A
  • Corticosterone 21-acetate
  • Corticosterone acetate
  • NSC 81764
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-
  • Skf 5654
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 3 products.
  • 2-((8S,9S,10R,11S,13S,14S,17S)-11-Hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17…
    Indagoo
    + Info

    2-((8S,9S,10R,11S,13S,14S,17S)-11-Hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate

    CAS:
    Formula:C23H32O5
    Purity:98%
    Color and Shape:Solid
    Molecular weight:388.4972

    Ref: IN-DA000E36

    1g
    292.00€
    5g
    To inquire
    50mg
    56.00€
    250mg
    130.00€
  • Corticosterone 21-Acetate
    TRC
    + Info

    Corticosterone 21-Acetate

    Controlled Product
    CAS:
    <p>Applications Corticosterone (C695700) derivative. An intermediate in the biosynthesis of aldosterone, isolated from the adrenal cortex.<br>References Schmidt, M., et al.: Endocrinol., 150, 2709 (2009), Bailey, M., et al.: J. Immunol., 182, 7888 (2009), Brunton, P., et al.: J. Neurosci., 29, 6449 (2009), Pruett, S., et al.: Toxicol. Sci., 109, 265 (2009),<br></p>
    Formula:C23H32O5
    Color and Shape:Off White
    Molecular weight:388.50

    Ref: TR-C695710

    100mg
    115.00€
  • Corticosterone 21-acetate
    Biosynth
    + Info

    Corticosterone 21-acetate

    Controlled Product
    CAS:
    <p>Corticosterone 21-acetate is a fatty acid that has been used as a pharmaceutical preparation for the treatment of high blood pressure. It also has antihypertensive activity and can be used to treat congestive heart failure. Corticosterone 21-acetate binds to the distal tubule cells in the kidney, causing an increase in the production of hydroxyproline, which leads to increased synthesis of collagen. This drug has been shown to inhibit the growth of some types of cancerous cells and may have synergistic interactions with other drugs that are used to treat cancer. Corticosterone 21-acetate is bound to corticosteroid binding globulin in the blood plasma, preventing it from crossing into tissues.</p>
    Formula:C23H32O5
    Purity:Min. 95%
    Color and Shape:Solid
    Molecular weight:388.5 g/mol

    Ref: 3D-FC20556

    25mg
    187.00€
    50mg
    290.00€