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CAS 1173-26-8

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Corticosterone acetate

Description:
Corticosterone acetate is a synthetic derivative of corticosterone, a steroid hormone produced by the adrenal cortex. It is classified as a glucocorticoid and is primarily used in research and therapeutic applications due to its anti-inflammatory and immunosuppressive properties. The substance appears as a white to off-white crystalline powder and is soluble in organic solvents such as ethanol and methanol, but has limited solubility in water. Its molecular structure includes a steroid backbone with an acetate group, which enhances its lipophilicity and bioavailability. Corticosterone acetate is often utilized in studies related to stress response, metabolism, and endocrine function. In laboratory settings, it may be administered to animal models to investigate its physiological effects or to develop treatments for conditions like autoimmune diseases and allergies. As with other glucocorticoids, caution is advised regarding its use, as it can lead to side effects such as hormonal imbalances and metabolic disturbances when used improperly.
Formula:C23H32O5
InChI:InChI=1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1
InChI key:InChIKey=WKQCPUMQBMFPLC-ZWFCQKKLSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(C[C@@H]3O)[C@@H](C(COC(C)=O)=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]
Synonyms:
  • (11Beta)-11-Hydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
  • (11β)-21-(Acetyloxy)-11-hydroxypregn-4-ene-3,20-dione
  • 11-Hydroxy-3,20-Dioxopregn-4-En-21-Yl Acetate
  • Cort A
  • Corticosterone 21-acetate
  • Corticosterone acetate
  • NSC 81764
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-
  • Skf 5654
Found 3 products.