CAS 1173797-55-1

Formula: C37H45N2O6P

InChI: InChI=1S/C37H45N2O6P/c1-8-32-25-35(45-46(43-24-12-23-38)39(27(2)3)28(4)5)36(44-32)26-42-37(29-13-10-9-11-14-29,30-15-19-33(40-6)20-16-30)31-17-21-34(41-7)22-18-31/h1,9-11,13-22,27-28,32,35-36H,12,24-26H2,2-7H3/t32-,35-,36+,46?/m0/s1

InChI key: SGSVNADNKJQVBP-OFEIKZNSSA-N

SMILES: CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)C#C

Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite

CAS: 1173797-55-1

Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite is a monophosphate nucleoside analog. The ethynyl group is attached to the 2'-hydroxyl group of the ribose sugar. This nucleotide analogue inhibits DNA and RNA synthesis by inhibiting DNA polymerase and RNA polymerase. Ethynyl 2-deoxy-5-O-DMT-ribosyl 3-CE phosphoramidite has antiviral activity against Herpes simplex virus type 1 (HSV1) and type 2 (HSV2) in vitro, as well as cytotoxic activity against human leukemia cells in vitro.

Formula: C₃₇H₄₅N₂O₆P

Purity: Min. 95%

Molecular weight: 644.74 g/mol

Ref: 3D-PE159680