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CAS 117467-28-4

:

Cefditoren Pivoxil

Description:
Cefditoren pivoxil is a broad-spectrum cephalosporin antibiotic used primarily for the treatment of bacterial infections. It is a prodrug, meaning it is converted into its active form, cefditoren, in the body. Cefditoren exhibits a high affinity for penicillin-binding proteins, which are essential for bacterial cell wall synthesis, thereby inhibiting bacterial growth. The substance is characterized by its stability against certain beta-lactamases, making it effective against a range of gram-positive and some gram-negative bacteria. Cefditoren pivoxil is typically administered orally and is well-absorbed, with its bioavailability enhanced by the presence of food. It is generally well-tolerated, though potential side effects may include gastrointestinal disturbances, allergic reactions, and alterations in liver function tests. The chemical structure includes a beta-lactam ring, which is a common feature of cephalosporins, contributing to its antibacterial properties. Overall, cefditoren pivoxil is an important therapeutic agent in the management of various infections, particularly respiratory tract infections.
Formula:C25H28N6O7S3
InChI:InChI=1/C25H28N6O7S3/c1-12-15(41-10-27-12)7-6-13-8-39-21-17(29-19(32)16(30-36-5)14-9-40-24(26)28-14)20(33)31(21)18(13)22(34)37-11-38-23(35)25(2,3)4/h6-7,9-10,17,21H,8,11H2,1-5H3,(H2,26,28)(H,29,32)/t17-,21-/m1/s1
InChI key:InChIKey=AFZFFLVORLEPPO-UVYJNCLZSA-N
SMILES:C(OCOC(C(C)(C)C)=O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1/C=C\C4=C(C)N=CS4)[H]
Synonyms:
  • 117467-28-4
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, [6R-[3(Z),6α,7β(Z)]]-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[(1Z)-2-(4-methyl-5-thiazolyl)ethenyl]-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-
  • Ccris 7768
  • Cefditoren pivaloyloxymethyl ester
  • Cefditoren pivoxyl
  • Cefditorin
  • Cefditran
  • Ceftorin
  • See more synonyms
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