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CAS 117946-91-5

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Luzindole

Description:
Luzindole is a synthetic compound primarily recognized for its role as a selective antagonist of melatonin receptors, particularly the MT2 receptor. It is characterized by its unique chemical structure, which includes a substituted indole moiety, contributing to its biological activity. Luzindole has been studied for its potential applications in sleep disorders and circadian rhythm regulation due to its ability to modulate melatonin signaling. The compound exhibits moderate solubility in organic solvents and is typically administered in research settings to investigate its pharmacological effects. In addition to its melatonin receptor antagonism, luzindole has been explored for its influence on various neurochemical pathways, making it a subject of interest in neuropharmacology. Safety and toxicity profiles are essential considerations in its use, as with any pharmacologically active substance. Overall, luzindole serves as a valuable tool in understanding melatonin's role in physiological processes and may have implications for therapeutic strategies targeting sleep and mood disorders.
Formula:C19H20N2O
InChI:InChI=1S/C19H20N2O/c1-14(22)20-12-11-17-16-9-5-6-10-18(16)21-19(17)13-15-7-3-2-4-8-15/h2-10,21H,11-13H2,1H3,(H,20,22)
InChI key:InChIKey=WVVXBPKOIZGVNS-UHFFFAOYSA-N
SMILES:C(CNC(C)=O)C=1C=2C(NC1CC3=CC=CC=C3)=CC=CC2
Synonyms:
  • 2-Benzyl-N-acetyltryptamine
  • Acetamide, N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]-
  • N-0774
  • N-Acetyl-2-Benzyltryptamine
  • N-[2-(2-benzyl-1H-indol-3-yl)ethyl]acetamide
  • N-[2-[2-(Phenylmethyl)-1H-Indol-3-Yl]Ethyl]Acetamide
  • N-[2-[2-(Phenylmethyl)-1H-indol-3-yl]ethyl]acetamide, N-Acetyl-2-benzyltryptamine
  • Luzindole
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