CAS 117976-90-6

Rabeprazole sodium

Description:

Rabeprazole sodium is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers by reducing stomach acid production. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH-dependent solubility profile. The chemical formula for rabeprazole sodium is C18H20N3NaO3S, and it has a molecular weight of approximately 366.43 g/mol. Rabeprazole sodium works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased gastric acid secretion. Its pharmacokinetics show rapid absorption, with peak plasma concentrations typically occurring within a few hours after oral administration. The drug is metabolized primarily in the liver, and its elimination half-life is relatively short, necessitating once-daily dosing for effective acid control. Common side effects may include headache, nausea, and gastrointestinal disturbances, but it is generally well-tolerated. Rabeprazole sodium is often favored for its efficacy and safety profile in managing acid-related disorders.

Formula: C₁₈H₂₁N₃O₃S·Na

InChI: InChI=1S/C18H21N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21);

InChI key: InChIKey=MLQSMKIAIQJZSZ-UHFFFAOYSA-N

SMILES: S(CC1=C(C)C(OCCCOC)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3.[Na]

Synonyms:

• (3,5-Dibromo-4-Hydroxyphenyl)(2-Ethyl-1-Benzofuran-3-Yl)Methanone
• 1H-Benzimidazole, 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-, sodium salt
• 1H-Benzimidazole, 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-, sodium salt (1:1)
• 2-[[[4-(3-Methoxypropoxy)-3-Methyl-2-Pyridinyl]Methyl]Sulfinyl]-1H-Benzimidazole, Sodium Salt
• 2-[[[4-(3-Methoxypropoxy)-3-Methylpyridin-2-Yl]Methyl]Sulfiny]-1H-Benzimidazole Sodium Salt
• 2-[[[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]-1H-benzimidazole sodium salt
• Aciphex
• E 3810
• LY 307640 sodium
• Pariet
• Pariprazole
• Pepcia
• Rabeprazole Sodium
• Rabeprazole, Sodium Salt
• Rabicip
• Sodium 2-({[4-(3-Methoxypropoxy)-3-Methylpyridin-2-Yl]Methyl}Sulfinyl)Benzimidazol-1-Ide
• Sodium 2-[[4-(3-Methoxypropoxy)-3-Methyl-Pyridin-2-Yl]Methylsulfinyl]Benzoimidazole
• Sodium Rabeprazole

Rabeprazole Sodium Salt

CAS: 117976-89-3, 117976-90-6

Formula: C₁₈H₂₀N₃NaO₃S

Purity: >98.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 381.43

Ref: 3B-R0115

Rabeprazole sodium

CAS: 117976-90-6

Formula: C₁₈H₂₀N₃NaO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 381.4245

Ref: IN-DA003U3W

Rabeprazole-d4 Sodium Salt

CAS: 117976-90-6

Formula: C₁₈H₁₆D₄N₃O₃S·Na

Color and Shape: Pale Yellow Solid

Molecular weight: 362.47 22.99

Ref: 4Z-R-204

Rabeprazole sodium

CAS: 117976-90-6

Rabeprazole sodium

Purity: ≥98%

Molecular weight: 381.42g/mol

Ref: 54-BUP13165

Rabeprazole Sodium Salt

CAS: 117976-90-6

Formula: C₁₈H₂₀N₃O₃S·Na

Color and Shape: Off-White Solid

Molecular weight: 358.44 22.99

Ref: 4Z-R-203

Rabeprazole-d4 Sodium Salt(benzimidazole-4,5,6,7-d4)

CAS: 117976-90-6

Purity: 99 atom % D

Color and Shape: Off White Solid

Molecular weight: 385.45

Ref: 3U-D6825

Rabeprazole Sodium

CAS: 117976-90-6

Color and Shape: Neat

Ref: 86-MM0618.01

Rabeprazole sodium

CAS: 117976-90-6

Rabeprazole sodium treats stomach ulcers and Zollinger-Ellison syndrome, blocking ATPase in gastric cells.

Formula: C₁₈H₂₀N₃NaO₃S

Purity: 98% - 99.912%

Color and Shape: White Or Off White Crystalline Powder

Molecular weight: 381.42

Ref: TM-T1651

Rabeprazole Sodium RS

CAS: 117976-90-6

Color and Shape: White To Pale Yellow-White Solid Powder

Ref: 2K-1179200021

Rabeprazole Sodium Salt

CAS: 117976-90-6

Stability Hygroscopic
Applications A partially reversible gastric proton pump inhibitor.
References Morii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993), Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994), Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)

Formula: C₁₈H₂₀N₃O₃S·Na

Color and Shape: Off-White

Molecular weight: 381.42

Ref: TR-R070500

Rabeprazole sodium salt - Bio-X ™

CAS: 117976-90-6

Rabeprazole is a proton pump inhibitor drug that is used to treat symptoms of GERD, heal gastrointestinal ulcers and eradicate Helicobacter pylori. This antiulcer drug suppresses gastric acid by inhibiting the gastric H+/K+ ATPase at the parietal cell.

Formula: C₁₈H₂₀N₃O₃SNa

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 381.43 g/mol

Ref: 3D-BR167318

Rabeprazole Na

CAS: 117976-90-6

Proton pump inhibitor; antiulcer drug

Formula: C₁₈H₂₀N₃O₃SNa

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 381.43 g/mol

Ref: 3D-IM57865

Rabeprazole-d3 Sodium Salt

Controlled Product

CAS: 117976-90-6

Stability Light Sensitive, Very Hygroscopic
Applications Labelled Rabeprazole (R070500). A partially reversible gastric proton pump inhibitor.
References Morii, M., and Takeguchi, N.: J. Biol. Chem., 268, 21553 (1993), Yasuda, S., et al.: Int. J. Clin. Pharmacol. Ther., 32, 466 (1994), Cloud, M.L., et al.: Dig. Dis. Sci., 43, 993 (1998)

Formula: C₁₈H₁₇D₃N₃NaO₃S

Color and Shape: Neat

Molecular weight: 384.44

Ref: TR-R070503