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CAS 117976-90-6

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Rabeprazole sodium

Description:
Rabeprazole sodium is a proton pump inhibitor (PPI) primarily used to treat conditions such as gastroesophageal reflux disease (GERD) and peptic ulcers by reducing stomach acid production. It is a white to off-white crystalline powder that is soluble in water and exhibits a pH-dependent solubility profile. The chemical formula for rabeprazole sodium is C18H20N3NaO3S, and it has a molecular weight of approximately 366.43 g/mol. Rabeprazole sodium works by irreversibly inhibiting the H+/K+ ATPase enzyme in the gastric parietal cells, leading to decreased gastric acid secretion. Its pharmacokinetics show rapid absorption, with peak plasma concentrations typically occurring within a few hours after oral administration. The drug is metabolized primarily in the liver, and its elimination half-life is relatively short, necessitating once-daily dosing for effective acid control. Common side effects may include headache, nausea, and gastrointestinal disturbances, but it is generally well-tolerated. Rabeprazole sodium is often favored for its efficacy and safety profile in managing acid-related disorders.
Formula:C18H21N3O3S·Na
InChI:InChI=1S/C18H21N3O3S.Na/c1-13-16(19-9-8-17(13)24-11-5-10-23-2)12-25(22)18-20-14-6-3-4-7-15(14)21-18;/h3-4,6-9H,5,10-12H2,1-2H3,(H,20,21);
InChI key:InChIKey=MLQSMKIAIQJZSZ-UHFFFAOYSA-N
SMILES:S(CC1=C(C)C(OCCCOC)=CC=N1)(=O)C=2NC=3C(N2)=CC=CC3.[Na]
Synonyms:
  • (3,5-Dibromo-4-Hydroxyphenyl)(2-Ethyl-1-Benzofuran-3-Yl)Methanone
  • 1H-Benzimidazole, 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-, sodium salt
  • 1H-Benzimidazole, 2-[[[4-(3-methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-, sodium salt (1:1)
  • 2-[[[4-(3-Methoxypropoxy)-3-Methyl-2-Pyridinyl]Methyl]Sulfinyl]-1H-Benzimidazole, Sodium Salt
  • 2-[[[4-(3-Methoxypropoxy)-3-Methylpyridin-2-Yl]Methyl]Sulfiny]-1H-Benzimidazole Sodium Salt
  • 2-[[[4-(3-Methoxypropoxy)-3-methylpyridin-2-yl]methyl]sulfinyl]-1H-benzimidazole sodium salt
  • Aciphex
  • E 3810
  • LY 307640 sodium
  • Pariet
  • See more synonyms
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