CAS 118072-93-8
:Zoledronic acid
Description:
Zoledronic acid is a bisphosphonate compound primarily used in the treatment of osteoporosis and other conditions involving bone metabolism, such as Paget's disease and certain cancers that metastasize to bone. It functions by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain or increase bone density. The chemical formula of zoledronic acid is C₇H₁₁N₂O₇P, and it features a phosphonate group, which is crucial for its biological activity. This compound is typically administered intravenously due to its poor oral bioavailability. Zoledronic acid has a high affinity for hydroxyapatite, the mineral component of bone, allowing it to effectively target areas of increased bone turnover. It is generally well-tolerated, although potential side effects can include flu-like symptoms, renal impairment, and, in rare cases, osteonecrosis of the jaw. As a potent inhibitor of bone resorption, zoledronic acid plays a significant role in managing conditions associated with excessive bone loss.
Formula:C5H10N2O7P2
InChI:InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14)
InChI key:InChIKey=XRASPMIURGNCCH-UHFFFAOYSA-N
SMILES:C(P(=O)(O)O)(P(=O)(O)O)(CN1C=CN=C1)O
Synonyms:- Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-
- Phosphonic acid, P,P′-[1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-
- P,P′-[1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis[phosphonic acid]
- (1-Hydroxy-2-imidazol-1-ylethylidene)diphosphonic acid
- Zoledronic acid
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Found 7 products.
Zoledronic Acid Monohydrate
CAS:Formula:C5H10N2O7P2·H2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:290.11Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-
CAS:Formula:C5H10N2O7P2Purity:98%Color and Shape:SolidMolecular weight:272.0896(1-Hydroxy-2-(1H-Imidazol-1-Yl)Ethane-1,1-Diyl)Diphosphonic Acid
CAS:<p>(1-Hydroxy-2-(1H-Imidazol-1-Yl)Ethane-1,1-Diyl)Diphosphonic Acid</p>Purity:99%Molecular weight:272.09g/molZoledronic Acid
CAS:Formula:C5H10N2O7P2Color and Shape:White To Off-White SolidMolecular weight:272.09Zoledronic Acid
CAS:<p>Zoledronic Acid (ZOL 446) 是一种含氮二磷酸盐，能抑制破骨细胞的分化和凋亡，具有高效的抗骨质再吸收活性，也有抗癌作用。</p>Formula:C5H10N2O7P2Purity:98% - 99.93%Color and Shape:White Crystalline PowderMolecular weight:272.09
![Phosphonic acid, [1-hydroxy-2-(1H-imidazol-1-yl)ethylidene]bis-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00HED6.jpg&w=3840&q=75)
