CAS 118292-40-3: Tazarotene

Description: Tazarotene is a synthetic retinoid, primarily used in dermatology for the treatment of acne and psoriasis. It functions as a topical agent, promoting cell turnover and reducing inflammation by modulating gene expression through its action on retinoic acid receptors. Tazarotene is characterized by its ability to bind selectively to RAR (retinoic acid receptors) and RXR (retinoid X receptors), influencing skin cell differentiation and proliferation. The compound is typically formulated as a cream or gel and is applied directly to the affected areas. Its chemical structure includes a bicyclic ring system, which is essential for its biological activity. Tazarotene is known for its potential side effects, including skin irritation, dryness, and photosensitivity, necessitating careful patient management and education regarding sun protection. As a member of the retinoid family, it shares some properties with other retinoids but is distinguished by its unique efficacy and safety profile in treating specific dermatological conditions.

Formula: C₂₁H₂₁NO₂S

InChI: InChI=1S/C21H21NO2S/c1-4-24-20(23)16-7-9-17(22-14-16)8-5-15-6-10-19-18(13-15)21(2,3)11-12-25-19/h6-7,9-10,13-14H,4,11-12H2,1-3H3

InChI key: InChIKey=OGQICQVSFDPSEI-UHFFFAOYSA-N

SMILES: O=C(OCC)C1=CN=C(C#CC2=CC=C3SCCC(C3=C2)(C)C)C=C1

Synonyms:

• AGN 190168
• 3-Pyridinecarboxylic acid, 6-[(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester
• 2H-1-Benzothiopyran, 3-pyridinecarboxylic acid deriv.
• Tazarotene
• 3-Pyridinecarboxylic acid, 6-[2-(3,4-dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-, ethyl ester

Tazarotene

CAS: 118292-40-3

• Formula: C₂₁H₂₁NO₂S
• Purity: >98.0%(GC)
• Color and Shape: White to Yellow to Green powder to crystal
• Molecular weight: 351.46

Tazarotene

CAS: 118292-40-3

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

• Formula: C₂₁H₂₁NO₂S
• Color and Shape: White Yellow Crystalline Powder
• Molecular weight: 351.1293

Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate

CAS: 118292-40-3

• Formula: C₂₁H₂₁NO₂S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 351.4619

Tazarotene

CAS: 118292-40-3

• Formula: C₂₁H₂₁NO₂S
• Color and Shape: Pale Yellow Solid
• Molecular weight: 351.46

Tazarotene

CAS: 118292-40-3

• Formula: C₂₁H₂₁NO₂S
• Molecular weight: 351.46

Tazarotene

CAS: 118292-40-3

• Formula: C₂₁H₂₁NO₂S
• Color and Shape: Neat
• Molecular weight: 351.46

Tazarotene

CAS: 118292-40-3

Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.

• Formula: C₂₁H₂₁NO₂S
• Purity: 97.01% - 99.14%
• Color and Shape: White Solid
• Molecular weight: 351.46

Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate

CAS: 118292-40-3

• Purity: 95.0%
• Molecular weight: 351.4599914550781

Tazarotene

CAS: 118292-40-3

Applications An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity …

• Formula: C₂₁H₂₁NO₂S
• Color and Shape: Light Yellow
• Molecular weight: 351.46

Tazarotene - Bio-X ™

CAS: 118292-40-3

Tazarotene is an acetylenic retinoid that is used for the treatment of wrinkles, pigmentation of …

• Formula: C₂₁H₂₁NO₂S
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 351.46 g/mol

Tazarotene

CAS: 118292-40-3

Binds retinoid acid receptors-γ and -β; topical treatment for skin disorders

• Formula: C₂₁H₂₁NO₂S
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 351.46 g/mol