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Retinoid Receptor

Retinoid Receptor

Retinoid Receptors are nuclear receptors that mediate the effects of retinoids (vitamin A derivatives) on gene expression. These receptors play a vital role in cell differentiation, proliferation, and apoptosis. Inhibitors of retinoid receptors are used to study their involvement in various diseases, including cancer, skin disorders, and metabolic conditions. By modulating retinoid receptor activity, these inhibitors can provide insights into the mechanisms of retinoid signaling and its therapeutic potential. At CymitQuimica, we provide retinoid receptor inhibitors to support your research in dermatology, oncology, and metabolic regulation.

Found 20 products for "Retinoid Receptor".

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    RXR agonist 3

    RXR agonist 3 (Compound 35) is a potent partial agonist of RXR, showing EC50 values of 3 nM for RXRα, 3 nM for RXRβ, and 8 nM for RXRγ. It is applicable in research related to Alzheimer's disease, multiple sclerosis, and lymphoma.

    Ref: TM-T214644

  • BMS 195614
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    BMS 195614

    CAS:
    BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.
    Formula:C29H24N2O3
    Purity:97.14%
    Color and Shape:White Solid
    Molecular weight:448.51

    Ref: TM-T22192

  • CD3254
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    CD3254

    CAS:
    CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.
    Formula:C24H28O3
    Purity:98.71% - 98.71%
    Color and Shape:Yellow Solid
    Molecular weight:364.48

    Ref: TM-T14912

  • AR7
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    AR7

    CAS:
    AR7 is a retinoic acid receptor α (RARα) antagonist.
    Formula:C15H12ClNO
    Purity:98.12% - 99.86%
    Color and Shape:White Solid
    Molecular weight:257.715

    Ref: TM-T3955

  • BMS270394
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    BMS270394

    CAS:
    BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.
    Formula:C23H26FNO4
    Color and Shape:White Solid
    Molecular weight:399.46

    Ref: TM-T26846

  • BMS 961
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    BMS 961

    CAS:
    BMS 961 is an RARγ-selective agonist used to profile coregulator binding signatures and to induce TSLP expression in mouse keratinocytes, supporting research on RARγ transcription and epithelial immune signaling.
    Formula:C23H26FNO4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:399.46

    Ref: TM-T22611

  • CD2665
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    CD2665

    CAS:
    CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.
    Formula:C31H34O5
    Purity:99.71%
    Color and Shape:White Solid
    Molecular weight:486.6

    Ref: TM-T14911

  • MM 11253
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    MM 11253

    CAS:
    MM 11253 is a RARγ antagonist with IC50 of 44nM.
    Formula:C28H30O2S2
    Purity:99.41%
    Color and Shape:Solid
    Molecular weight:462.67

    Ref: TM-T23005

  • BMS 753
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    BMS 753

    CAS:
    BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).
    Formula:C21H21NO4
    Purity:98.55%
    Color and Shape:Solid
    Molecular weight:351.4

    Ref: TM-T22049

  • AC-261066
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    AC-261066

    CAS:
    AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.
    Formula:C17H20FNO4S
    Purity:99.64%
    Color and Shape:Solid
    Molecular weight:353.41

    Ref: TM-T14089

  • Ch55
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    Ch55

    CAS:
    Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.
    Formula:C24H28O3
    Purity:99.55%
    Color and Shape:Solid
    Molecular weight:364.48

    Ref: TM-T14946

  • Fluorobexarotene
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    Fluorobexarotene

    CAS:
    Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.
    Formula:C24H27FO2
    Purity:99.08%
    Color and Shape:Solid
    Molecular weight:366.4684

    Ref: TM-T11303

  • BMS641
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    BMS641

    CAS:
    BMS641 (BMS-209641) is a RARβ agonist with affinity for RARβ that synergistically activates RARβ and RARgamma to induce cell maturation.
    Formula:C27H23ClO2
    Purity:98.11%
    Color and Shape:Solid
    Molecular weight:414.92

    Ref: TM-T26854

  • KCL-286
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    KCL-286

    CAS:
    KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).
    Formula:C19H14N2O4
    Purity:99.88%
    Color and Shape:Solid
    Molecular weight:334.33

    Ref: TM-T78575

  • ER 50891
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    ER 50891

    CAS:
    ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.
    Formula:C29H24N2O2
    Purity:99.43%
    Color and Shape:Solid
    Molecular weight:432.51

    Ref: TM-T22767

  • LE135
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    LE135

    CAS:
    LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).
    Formula:C29H30N2O2
    Purity:97.94%
    Color and Shape:Solid
    Molecular weight:438.56

    Ref: TM-T22920

  • ZSH-2208
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    ZSH-2208

    CAS:
    ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.
    Formula:C20H18O3S
    Purity:99.81%
    Color and Shape:Solid
    Molecular weight:338.42

    Ref: TM-T205434

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    BMS-948

    CAS:
    BMS-948 is a selective RARβ transcriptional agonist with an EC50 of 0.1 μM. It is utilized in research pertaining to tumor diseases, embryonic development, and tissue remodeling.
    Formula:C24H17NO3
    Molecular weight:367.40

    Ref: TM-T218334

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    LE-540

    CAS:
    LE-540 is a selective retinoic acid receptor β (RARβ) antagonist with a Ki value of 0.22 μM. It shows potential for use in cancer research, particularly in studies focusing on breast and lung cancer.
    Formula:C33H32N2O2
    Molecular weight:488.63

    Ref: TM-T213143

  • BMS453
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    BMS453

    CAS:
    BMS453 (BMS-189453), a synthetic retinoid, is a potent and selective agonist of RARβ and a potent testicular toxin.
    Formula:C27H24O2
    Purity:99.93%
    Color and Shape:White Solid
    Molecular weight:380.48

    Ref: TM-T21714