Description:Tyrphostin AG 126 is a synthetic compound known for its role as a selective inhibitor of receptor tyrosine kinases, particularly the epidermal growth factor receptor (EGFR). It is classified as a small molecule and is often utilized in biochemical research to study signal transduction pathways and cellular processes influenced by tyrosine phosphorylation. The compound exhibits characteristics typical of tyrosine kinase inhibitors, including the ability to interfere with cell proliferation and survival in various cancer cell lines. Tyrphostin AG 126 is typically characterized by its moderate solubility in organic solvents and limited solubility in water, which can affect its bioavailability in experimental settings. Its chemical structure features a phenyl group and a substituted imidazole, contributing to its binding affinity for target kinases. Researchers often employ this compound in studies related to cancer biology, drug development, and the exploration of therapeutic strategies targeting tyrosine kinase-mediated signaling pathways. As with many chemical substances, safety precautions should be observed when handling Tyrphostin AG 126 in laboratory environments.
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