MAPK
MAPKs are a family of protein kinases involved in a variety of cellular processes, including growth, proliferation, differentiation, and stress responses. The MAPK signaling pathway consists of several tiers, including ERK, JNK, and p38 MAPKs, each playing distinct roles in cellular function. Dysregulation of MAPK signaling is linked to cancer, inflammatory diseases, and metabolic disorders. At CymitQuimica, we offer a wide array of MAPK inhibitors and activators to support your research in cell biology, signal transduction, and disease mechanisms.
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Ravoxertinib hydrochloride
CAS:2070009-58-2
Ravoxertinib hydrochloride is an orally bioavailable and selective inhibitor for ERK kinase activity (IC50: 6.1 …
Formula:
C21H19Cl2FN6O2
Purity:
98%
Color and Shape:
Solid
Molecular weight:
477.32
Ref: TM-T15377
| 1mg | 46.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
Alpinumisoflavone
CAS:34086-50-5
Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and …
Formula:
C20H16O5
Color and Shape:
Solid
Molecular weight:
336.34
Ref: TM-TN3397
| 1mg | 154.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
Omtriptolide
CAS:195883-06-8
Omtriptolide, triptolide purified from the Chinese herb, is a water-soluble derivative prodrug.
Formula:
C24H28O9
Purity:
98%
Color and Shape:
Solid
Molecular weight:
460.479
Ref: TM-T16390
| 1mg | 136.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
Dilmapimod
CAS:444606-18-2
Dilmapimod (SB-681323) is a potent inhibitor of p38 MAPK ,it potentially suppresses inflammation in chronic …
Formula:
C23H19F3N4O3
Purity:
97.53%
Color and Shape:
Solid
Molecular weight:
456.42
Ref: TM-T12850
| 5mg | 47.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 350.00 € | ||
| 1mL*10mM (DMSO) | 50.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
Regorafénib N-oxyde (M2)
CAS:835621-11-9
Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.
Formula:
C21H15ClF4N4O4
Purity:
98.03% - 99.48%
Color and Shape:
Solid
Molecular weight:
498.81
Ref: TM-T10157
| 1mg | 44.00 € | ||
| 2mg | 56.00 € | ||
| 5mg | 80.00 € | ||
| 10mg | 103.00 € | ||
| 25mg | 180.00 € | ||
| 50mg | 324.00 € | ||
| 100mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 88.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
CC-90003
CAS:1621999-82-3
CC-90003 is a selective inhibitor of ERK 1/2. It has antitumor activity.
Formula:
C22H21F3N6O2
Purity:
99.42%
Color and Shape:
Solid
Molecular weight:
458.44
Ref: TM-T14894
| 1mg | 48.00 € | ||
| 5mg | 88.00 € | ||
| 10mg | 137.00 € | ||
| 25mg | 264.00 € | ||
| 50mg | 376.00 € | ||
| 100mg | 562.00 € | ||
| 1mL*10mM (DMSO) | 89.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
MRTX-1257
CAS:2206736-04-9
MRTX-1257: selective, irreversible KRAS G12C inhibitor; IC50 of 900 pM; 31% bioavailable in mice; 77% …
Formula:
C33H39N7O2
Purity:
96.59% - 99.07%
Color and Shape:
Solid
Molecular weight:
565.71
Ref: TM-T16143
| 1mg | 64.00 € | ||
| 2mg | 89.00 € | ||
| 5mg | 131.00 € | ||
| 10mg | 220.00 € | ||
| 25mg | 371.00 € | ||
| 50mg | 557.00 € | ||
| 100mg | 797.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
AX-15836
CAS:2035509-96-5
AX-15836 is an inhibitor of ERK5 (IC50 : 8 nM).
Formula:
C32H40N8O5S
Purity:
98.96%
Color and Shape:
Solid
Molecular weight:
648.78
Ref: TM-T14360
| 1mg | 57.00 € | ||
| 2mg | 81.00 € | ||
| 5mg | 120.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 298.00 € | ||
| 50mg | 424.00 € | ||
| 100mg | 597.00 € | ||
| 500mg | 1,225.00 € | ||
| 1mL*10mM (DMSO) | 167.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
GW806742X
CAS:579515-63-2
GW806742X inhibits MLKL with Kd 9.3 μM, preventing necroptosis; also targets VEGFR2.
Formula:
C25H22F3N7O4S
Purity:
98.30%
Color and Shape:
Solid
Molecular weight:
573.55
Ref: TM-T11520
| 2mg | 35.00 € | ||
| 5mg | 51.00 € | ||
| 10mg | 70.00 € | ||
| 25mg | 119.00 € | ||
| 50mg | 188.00 € | ||
| 100mg | 349.00 € | ||
| 1mL*10mM (DMSO) | 66.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
LXH254
CAS:1800398-38-2
LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM …
Formula:
C25H25F3N4O4
Purity:
98.3% - 99.92%
Color and Shape:
Solid
Molecular weight:
502.49
Ref: TM-T11898
| 1mg | 52.00 € | ||
| 5mg | 122.00 € | ||
| 10mg | 185.00 € | ||
| 25mg | 363.00 € | ||
| 50mg | 567.00 € | ||
| 100mg | 690.00 € | ||
| 200mg | 948.00 € | ||
| 500mg | 1,444.00 € | ||
| 1mL*10mM (DMSO) | 135.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
ARS-1630
CAS:1698055-86-5
ARS-1630 is a mutant K-ras G12C inhibitor. It is a less active enantiomer of ARS-1620.
Formula:
C21H17ClF2N4O2
Purity:
97.81%
Color and Shape:
Solid
Molecular weight:
430.84
Ref: TM-T10376
| 1mg | 52.00 € | ||
| 5mg | 117.00 € | ||
| 10mg | 170.00 € | ||
| 25mg | 325.00 € | ||
| 50mg | 469.00 € | ||
| 100mg | 615.00 € | ||
| 1mL*10mM (DMSO) | 134.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
K-Ras G12C-IN-4
CAS:2376328-55-9
K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。
Formula:
C31H33ClN4O4
Purity:
99.00%
Color and Shape:
Solid
Molecular weight:
561.07
Ref: TM-T11738
| 1mg | 74.00 € | ||
| 5mg | 170.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 424.00 € | ||
| 50mg | 562.00 € | ||
| 100mg | 827.00 € | ||
| 200mg | 1,111.00 € | ||
| 1mL*10mM (DMSO) | 202.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
AZD7624
CAS:1095004-78-6
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
Formula:
C27H30FN5O3
Purity:
99.37%
Color and Shape:
Solid
Molecular weight:
491.56
Ref: TM-T14381
| 1mg | 73.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 507.00 € | ||
| 50mg | 737.00 € | ||
| 100mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
LUT014
CAS:2274819-46-2
LUT014 is a B-Raf inhibitor (IC50: 11.7 nM) and developed to decrease dose-limiting acneiform lesions …
Formula:
C27H19F3N8O
Purity:
99.03%
Color and Shape:
Solid
Molecular weight:
528.49
Ref: TM-T15794
| 1mg | 66.00 € | ||
| 5mg | 142.00 € | ||
| 10mg | 188.00 € | ||
| 25mg | 346.00 € | ||
| 50mg | 487.00 € | ||
| 100mg | 682.00 € | ||
| 1mL*10mM (DMSO) | 166.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
Methylthiouracil
CAS:56-04-2
Methylthiouracil (NSC-193526) is a thiourea antithyroid agent that inhibits the synthesis of thyroid hormone, and …
Formula:
C5H6N2OS
Purity:
100% - 99.89%
Color and Shape:
Crystals Saturated Aqueous Solution Is Neutral Or Slightly Acidic (Ntp 1992)
Molecular weight:
142.18
Ref: TM-T0304
| 25mg | 48.00 € | ||
| 50mg | 55.00 € | ||
| 100mg | 81.00 € | ||
| 200mg | 127.00 € | ||
| 1mL*10mM (DMSO) | 55.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
BI-3406
CAS:2230836-55-0
BI-3406 is an orally active, highly potent and selective between KRAS and Son of Sevenless …
Formula:
C23H25F3N4O3
Purity:
99.20% - 99.66%
Color and Shape:
Solid
Molecular weight:
462.46
Ref: TM-T12979
| 1mg | 73.00 € | ||
| 5mg | 160.00 € | ||
| 10mg | 250.00 € | ||
| 25mg | 464.00 € | ||
| 50mg | 663.00 € | ||
| 100mg | 919.00 € | ||
| 500mg | 1,833.00 € | ||
| 1mL*10mM (DMSO) | 170.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
SU3327
CAS:40045-50-9
SU3327 (halicin) is a potent, selective and substrate-competitive inhibitor of JNK(IC50 of 0.7 μM).
Formula:
C5H3N5O2S3
Purity:
98.39%
Color and Shape:
Solid
Molecular weight:
261.3
Ref: TM-T13018
| 2mg | 38.00 € | ||
| 5mg | 65.00 € | ||
| 10mg | 96.00 € | ||
| 25mg | 173.00 € | ||
| 50mg | 311.00 € | ||
| 100mg | 472.00 € | ||
| 1mL*10mM (DMSO) | 87.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
Tanzisertib
CAS:899805-25-5
Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1/2/3 with IC50s of 61/7/6 nM, respectively, …
Formula:
C21H23F3N6O2
Purity:
98.66% - 99.28%
Color and Shape:
Solid
Molecular weight:
448.44
Ref: TM-T14895
| 1mg | 42.00 € | ||
| 5mg | 87.00 € | ||
| 10mg | 145.00 € | ||
| 25mg | 283.00 € | ||
| 50mg | 558.00 € | ||
| 100mg | 743.00 € | ||
| 200mg | 1,026.00 € | ||
| 1mL*10mM (DMSO) | 96.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
HI-TOPK-032
CAS:487020-03-1
HI-TOPK-032 is an effective and specific inhibitor of TOPK.
Formula:
C20H11N5OS
Purity:
98.52%
Color and Shape:
Solid
Molecular weight:
369.4
Ref: TM-T15481
| 2mg | 47.00 € | ||
| 5mg | 69.00 € | ||
| 10mg | 93.00 € | ||
| 25mg | 188.00 € | ||
| 50mg | 320.00 € | ||
| 100mg | 550.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
PF-3644022
CAS:1276121-88-0
PF-3644022 is a selective MK2 inhibitor, effective against TNFα (IC50: 5.2 nM, Ki: 3 nM), …
Formula:
C21H18N4OS
Purity:
98.13%
Color and Shape:
Solid
Molecular weight:
374.46
Ref: TM-T16501
| 1mg | 37.00 € | ||
| 5mg | 111.00 € | ||
| 10mg | 202.00 € | ||
| 25mg | 416.00 € | ||
| 50mg | 620.00 € | ||
| 100mg | 832.00 € | ||
| 500mg | 1,663.00 € | ||
| 1mL*10mM (DMSO) | 187.00 € |
Estimated delivery in United States, on Tuesday 27 May 2025
