CAS 1184914-03-1

Formula: C11H11N3OS

InChI: InChI=1S/C11H11N3OS/c1-7-4-2-3-5-8(7)14-10(15)9-6-13-11(12)16-9/h2-6H,1H3,(H2,12,13)(H,14,15)

InChI key: HVVKMORRBPMRDO-UHFFFAOYSA-N

SMILES: CC1=CC=CC=C1NC(=O)C2=CN=C(S2)N

2-Amino-N-(o-tolyl)-thiazole-5-carboxamide

Controlled Product

CAS: 1184914-03-1

Applications 2-Amino-N-(o-tolyl)-thiazole-5-carboxamide is an impurity of the anti-cancer drug Dasatinib (D193600). Dasatinib is a new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.
References Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004); Shah, N. P., et al.: Science, 305, 399 (2004); O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2006)

Formula: C₁₁H₁₁N₃OS

Color and Shape: Neat

Molecular weight: 233.06228

Ref: TR-A630528

Dasatinib Impurity 8

CAS: 1184914-03-1

Formula: C₁₁H₁₁N₃OS

Molecular weight: 233.29

Ref: ST-EA-CP-D1016