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Tris(hydroxymethyl)aminomethane hydrochloride

CAS 1185-53-1: Tris(hydroxymethyl)aminomethane hydrochloride

Description:Tris(hydroxymethyl)aminomethane hydrochloride, commonly known as Tris hydrochloride, is a white crystalline powder that is highly soluble in water. It is a buffering agent widely used in biochemistry and molecular biology to maintain a stable pH in various biological and chemical reactions. The compound features three hydroxymethyl groups attached to an amino group, which contributes to its buffering capacity, particularly in the physiological pH range. Tris hydrochloride is often utilized in the preparation of buffers for electrophoresis, cell culture, and enzyme assays. Its pKa value is around 8.1, making it effective for buffering solutions near neutral pH. Additionally, Tris hydrochloride is relatively non-toxic and has low reactivity, which makes it suitable for use in sensitive biological applications. However, it is important to note that Tris can interfere with certain assays, particularly those involving phenolic compounds. Proper handling and storage conditions should be observed to maintain its stability and effectiveness.

Formula:C4H11NO3·ClH

InChI:InChI=1S/C4H11NO3.ClH/c5-4(1-6,2-7)3-8;/h6-8H,1-3,5H2;1H

InChI key:InChIKey=QKNYBSVHEMOAJP-UHFFFAOYSA-N

SMILES:Cl.OCC(N)(CO)CO

  • Synonyms:
  • 1,3-Propanediol, 2-Amino-2-(Hydroxymethyl)-, Chloride
  • 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride (1:1)
  • 1,3-Propanediol,2-amino-2-(hydroxymethyl)-,hydrochloride
  • 2-Amino-2-(Hidroximetil)Propano-1,3-Diol, Clorhidrato
  • 2-Amino-2-(Hydroxymethyl)-1,3-Propanediol, Hydrochloride
  • 2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol Hydrochloride
  • 2-Amino-2-(Hydroxymethyl)Propane-1,3-Diol Hydrochloride (1:1)
  • 2-Amino-2-(hydroxymethyl)propan-1,3-diolhydrochlorid
  • 2-Amino-2-(hydroxymethyl)propane-1,3-diol, chlorhydrate
  • 3-Propanediol,2-Amino-2-(Hydroxymethyl)-Hydrochloride
  • See more synonyms
  • Mole-Ready-Tris
  • Propane-1,3-Diol, 2-Amino-2-(Hydroxymethyl)-, Hydrochloride
  • Spectris(R) Hydrochloride
  • Spectris(Tm) Hydrochloride
  • T 6666
  • TRIZMA Hydrochloride
  • Tri(hydroxymethyl)aminomethane hydrochloride
  • Tris Hydrochloride
  • Tris chloride
  • Tris(hydroxymethyl)amino methane Hydrochloride
  • Tris(hydroxymethyl)aminoethane hydrochloride
  • Tris(hydroxymethyl)aminomethane hydrochloride
  • Tris-hydrochloric acid
  • Tris.HCl
  • Tris・Hcl
  • Trizmahydrochloride(Trishydrochloride)
  • Tromethamine hydrochloride
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BrandProduct dataPurityPrice rangeEstimated delivery
TCI logo
Tris(hydroxymethyl)aminomethane Hydrochloride
REF: 3B-T0740
CAS: 1185-53-1
>98.0%(N)28.00 €~170.00 €Mon 07 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris(hydroxymethyl)aminomethane hydrochloride, 99+%
REF: 02-A11379
CAS: 1185-53-1
99+%33.00 €~285.00 €Tue 08 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris(hydroxymethyl)aminomethane hydrochloride, 1M stock soln, pH 8.0
REF: 02-J63636
CAS: 1185-53-1
- - -86.00 €Tue 08 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris-HCl, 1M Solution, pH 8.0, Molecular Biology Grade, Ultrapure
REF: 02-J22638
CAS: 1185-53-1
- - -To inquireTue 08 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris(hydroxymethyl)aminomethane hydrochloride, 1M soln., pH 8.0, RNase free
REF: 02-J60080
CAS: 1185-53-1
- - -87.00 €Tue 08 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris(hydroxymethyl)aminomethane hydrochloride, 1M soln., pH 7,4, RNase free
REF: 02-J62848
CAS: 1185-53-1
- - -76.00 €Tue 08 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris-HCl, 0.5M buffer soln., pH 7.4, low endotoxin
REF: 02-J67501
CAS: 1185-53-1
- - -73.00 €~118.00 €Tue 08 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris-HCl, 0.5M buffer soln., pH 8.0, low endotoxin
REF: 02-J67510
CAS: 1185-53-1
- - -64.00 €~107.00 €Tue 08 Apr 25
Alfa Aesar By Thermo Fisher Scientific logo
Tris(hydroxymethyl)aminomethane hydrochloride, Molecular Biology Grade, 99+%
REF: 02-J67233
CAS: 1185-53-1
99+%68.00 €Tue 08 Apr 25
Indagoo logo
1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride
REF: IN-DA00HEKS
CAS: 1185-53-1
98%21.00 €~294.00 €Mon 14 Apr 25
Cygnus logo
Bovine Transferrin Standard E
REF: 5M-F121E-1
CAS:
- - -711.00 €Tue 15 Apr 25
Glentham logo
TRIS hydrochloride, 0.01M solution with 0.05M NaCl (pH 8.0)
REF: 7W-GB3987
CAS: 1185-53-1
- - -To inquireTue 15 Apr 25
Glentham logo
TRIS hydrochloride, 1M solution (pH 7.4)
REF: 7W-GE8151
CAS: 1185-53-1
- - -To inquireTue 15 Apr 25
Cygnus logo
BSA Standard E
REF: 5M-F031E-1
CAS:
- - -711.00 €Tue 15 Apr 25
Cygnus logo
Sample Diluent
REF: 5M-I094
CAS:
- - -269.00 €~1,196.00 €Tue 15 Apr 25
Apollo Scientific logo
Trometamol hydrochloride
REF: 54-BUP18127
CAS: 1185-53-1
99.39%50.00 €Tue 15 Apr 25
Cygnus logo
Anti-Protein A:HRP, 12 ml
REF: 5M-F911-12
CAS:
- - -586.00 €Tue 15 Apr 25
Cygnus logo
Bovine IgG Standard E
REF: 5M-F073E-1
CAS:
- - -887.00 €Tue 15 Apr 25
Cygnus logo
Anti-HEK 293:HRP Conjugate
REF: 5M-F651S-12
CAS:
- - -1,047.00 €Tue 15 Apr 25
Cygnus logo
HeLa HCP Standards Set, A-H
REF: 5M-F813
CAS:
- - -887.00 €Tue 15 Apr 25
discount label

Tris(hydroxymethyl)aminomethane Hydrochloride

CAS:1185-53-1

Ref: 3B-T0740

25g28.00 €
500g170.00 €
Estimated delivery in United States, on Monday 7 Apr 2025
discount label

Tris(hydroxymethyl)aminomethane hydrochloride, 99+%

CAS:1185-53-1

Ref: 02-A11379

1kg285.00 €
50g33.00 €
250g106.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

Tris(hydroxymethyl)aminomethane hydrochloride, 1M stock soln, pH 8.0

CAS:1185-53-1

Ref: 02-J63636

1l86.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

Tris-HCl, 1M Solution, pH 8.0, Molecular Biology Grade, Ultrapure

CAS:1185-53-1

Ref: 02-J22638

1lTo inquire
100mlTo inquire
500mlTo inquire
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

Tris(hydroxymethyl)aminomethane hydrochloride, 1M soln., pH 8.0, RNase free

CAS:1185-53-1

Ref: 02-J60080

250ml87.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

Tris(hydroxymethyl)aminomethane hydrochloride, 1M soln., pH 7,4, RNase free

CAS:1185-53-1

Ref: 02-J62848

250ml76.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

Tris-HCl, 0.5M buffer soln., pH 7.4, low endotoxin

CAS:1185-53-1

Ref: 02-J67501

100ml73.00 €
250ml118.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

Tris-HCl, 0.5M buffer soln., pH 8.0, low endotoxin

CAS:1185-53-1

Ref: 02-J67510

100ml64.00 €
250ml107.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

Tris(hydroxymethyl)aminomethane hydrochloride, Molecular Biology Grade, 99+%

CAS:1185-53-1

Ref: 02-J67233

100g68.00 €
Estimated delivery in United States, on Tuesday 8 Apr 2025
discount label

1,3-Propanediol, 2-amino-2-(hydroxymethyl)-, hydrochloride

CAS:1185-53-1

Ref: IN-DA00HEKS

5g22.00 €
1kg105.00 €
25g21.00 €
5kg294.00 €
100g27.00 €
500g56.00 €
Estimated delivery in United States, on Monday 14 Apr 2025
discount label

Ref: 5M-F121E-1

1ml711.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

TRIS hydrochloride, 0.01M solution with 0.05M NaCl (pH 8.0)

CAS:1185-53-1

Ref: 7W-GB3987

Undefined sizeTo inquire
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

Ref: 7W-GE8151

Undefined sizeTo inquire
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

BSA Standard E


Ref: 5M-F031E-1

1ml711.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

Sample Diluent


Ref: 5M-I094

100ml269.00 €
500ml711.00 €
1000ml1,196.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

Trometamol hydrochloride

CAS:1185-53-1

Ref: 54-BUP18127

500mg50.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

Anti-Protein A:HRP, 12 ml


Ref: 5M-F911-12

12ml586.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

Bovine IgG Standard E


Ref: 5M-F073E-1

1ml887.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

Anti-HEK 293:HRP Conjugate


Ref: 5M-F651S-12

12ml1,047.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
discount label

HeLa HCP Standards Set, A-H


Ref: 5M-F813

1ml887.00 €
Estimated delivery in United States, on Tuesday 15 Apr 2025
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