CAS 1185035-71-5

Formula: C18H14F4N2O4S

InChI: InChI=1S/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)/i3D,4D,6D,7D

InChI key: LKJPYSCBVHEWIU-ZDPIWEEJSA-N

SMILES: [2H]C1=C(C(=C(C(=C1F)[2H])[2H])S(=O)(=O)CC(C)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O)[2H]

Bicalutamide-d4

CAS: 1185035-71-5

Formula: C₁₈H₁₀D₄F₄N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 434.40

Ref: 4Z-B-022

Bicalutamide-d4

Controlled Product

CAS: 1185035-71-5

Applications Used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0)
References Tucker, H., et al.: J. Med. Chem., 31, 954 (1988), Cockshott, I.D., et al.: Eur. Urol., 18, Suppl. 3, 10 (1990), Cockshott, I., et al.: Br. J. Clin. Pharm., 36, 339 (1993), McKillop, D., et al.: Xenobiotica, 25, 623 (1995),

Formula: C₁₈H₁₀D₄F₄N₂O₄S

Color and Shape: Neat

Molecular weight: 434.4

Ref: TR-B382002

Bicalutamide-[d4]

CAS: 1185035-71-5

Ref: BE-MD-7237

Bicalutamide-d4

Controlled Product

CAS: 1185035-71-5

Bicalutamide-d4 is a monocarboxylic acid that is a competitive inhibitor of androgens. It binds to the cytosolic receptor and blocks the action of dihydrotestosterone (DHT). Bicalutamide-d4 has been shown to be effective in reducing prostate cancer tumour growth, but not in treating prostate cancer. This drug is non-steroidal and acts as an antagonist of androgen receptors. Bicalutamide-d4 has been shown to induce the production of monocarboxylic acid metabolites such as sulfone and amide, which have anti-inflammatory effects on tissues.

Formula: C₁₈H₁₀D₄F₄N₂O₄S

Purity: Min. 95%

Molecular weight: 434.4 g/mol

Ref: 3D-KXB03571