CAS 1185237-51-7

Panobinostat-d8 (Major) Hydrochloride Salt

Controlled Product

CAS: 1185237-51-7, 404950-80-7

Applications The novel labelled histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells.
References Claus, R., et al.: Oncogene, 22, 6489 (2003), Johnstone, R., et al.: Cancer Cell., 4, 13 (2003), Ying, J., et al.: Clin. Cancer Res., 11, 6442 (2005), Catley, L., et al.: Blood, 108, 3441 (2006), Steinberg, M., et al.: Clin. Ther., 29, 2289 (2007),

Formula: C₂₁H₁₆D₈ClN₃O₂

Color and Shape: Neat

Molecular weight: 393.94

Ref: TR-P180502