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CAS 1185255-99-5

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2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil

Description:
2-Desethoxy-2-hydroxy-1H-1-Ethyl Candesartan Cilexetil is a chemical compound that belongs to the class of angiotensin II receptor antagonists, which are primarily used in the treatment of hypertension and heart failure. This compound is a derivative of candesartan cilexetil, characterized by the removal of an ethoxy group and the introduction of a hydroxy group, which may influence its pharmacological properties. It typically exhibits high affinity for the angiotensin II receptor, leading to vasodilation and reduced blood pressure. The molecular structure includes a biphenyl moiety, which is common in many antihypertensive agents, contributing to its biological activity. The compound is usually administered in a prodrug form, which is converted into its active form in the body. Its solubility, stability, and bioavailability are critical factors that determine its effectiveness as a therapeutic agent. As with many pharmaceuticals, safety and efficacy profiles are established through clinical studies, and potential side effects may include dizziness, fatigue, or gastrointestinal disturbances.
Formula:C33H34N6O6
Synonyms:
  • Candygram
  • 3-[[2'-(1-Ethyl-1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-2,3-dihydro-1H-benzimidazole-4-carboxylic acid 2-oxo-1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester
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