CAS: 1187431-43-1 - Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1′-sulfinylbis[methane] (1:1)

Formula: C₂₆H₂₃FIN₅O₄·C₂H₆OS

InChI: InChI=1S/C26H23FIN5O4.C2H6OS/c1-13-22-21(23(31(3)24(13)35)30-20-10-7-15(28)11-19(20)27)25(36)33(17-8-9-17)26(37)32(22)18-6-4-5-16(12-18)29-14(2)34;1-4(2)3/h4-7,10-12,17,30H,8-9H2,1-3H3,(H,29,34);1-2H3

InChI key: InChIKey=OQUFJVRYDFIQBW-UHFFFAOYSA-N

SMILES: O=C1C2=C(NC3=CC=C(I)C=C3F)N(C(=O)C(=C2N(C(=O)N1C4CC4)C=5C=CC=C(C5)NC(=O)C)C)C.O=S(C)C

Synonyms:

• Acetamide, N-[3-[3-cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]-, compd. with 1,1′-sulfinylbis[methane] (1:1)
• Gsk 1120212B
• Trametinib DMSO
• Trametinib dimethyl sulfoxide

GSK1120212 (DMSO solvate)

CAS: 1187431-43-1

• Formula: C₂₈H₂₉FIN₅O₅S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 693.5282

Trametinib Dimethyl Sulfoxide

CAS: 1187431-43-1

• Formula: C₂₆H₂₃FIN₅O₄·C₂H₆OS
• Color and Shape: Off-White Solid
• Molecular weight: 615.40 78.13

Trametinib

CAS: 1187431-43-1

• Formula: C₂₆H₂₃FIN₅O₄
• Purity: (HPLC) ≥ 98.0%
• Color and Shape: White to off-white solid powder
• Molecular weight: 615.39

Trametinib (DMSO solvate)

CAS: 1187431-43-1

Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that …

• Formula: C₂₈H₂₉FIN₅O₅S
• Purity: 100% - 99.71%
• Color and Shape: Solid
• Molecular weight: 693.53

Trametinib (DMSO Solvate)

CAS: 1187431-43-1

Applications Trametinib (DMSO Solvate) is a highly potent and selective MEK inhibitor with significant antitumor …

• Formula: C₂₆H₂₃FIN₅O₄·C₂H₆OS
• Color and Shape: White
• Molecular weight: 693.53

GSK 1120212B

CAS: 1187431-43-1

Inhibits MEK1 and MEK2 kinases; targeted therapy for melanoma

• Formula: C₂₆H₂₃FIN₅O₄•C₂H₆OS
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 693.53 g/mol