CAS 1188296-52-7

3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Description:

3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a chemical compound characterized by its complex structure, which includes a pyrazolo[3,4-d]pyrimidine core, a tetrahydro-2H-pyran moiety, and a chlorophenoxy group. This compound is typically classified as a heterocyclic organic molecule, featuring multiple functional groups that contribute to its potential biological activity. The presence of the pyrazolo and pyrimidine rings suggests possible applications in medicinal chemistry, particularly in the development of pharmaceuticals targeting various biological pathways. The chlorophenoxy group may enhance lipophilicity and influence the compound's interaction with biological targets. Additionally, the tetrahydro-2H-pyran structure can provide stability and may affect the compound's solubility and permeability. Overall, this compound's unique structural features make it a subject of interest for research in drug development and other chemical applications.

Formula: C₁₇H₁₈ClN₅O₂

InChI: InChI=1S/C17H18ClN5O2/c18-11-2-1-3-13(8-11)25-9-14-15-16(19)20-10-21-17(15)23(22-14)12-4-6-24-7-5-12/h1-3,8,10,12H,4-7,9H2,(H2,19,20,21)

InChI key: InChIKey=AUMDBEHGJRZSOO-UHFFFAOYSA-N

SMILES: C(OC1=CC(Cl)=CC=C1)C=2C=3C(N(N2)C4CCOCC4)=NC=NC3N

Synonyms:

• 3-[(3-Chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-
• PF 4800567

PF-4800567

CAS: 1188296-52-7

PF-4800567

Formula: C₁₇H₁₈ClN₅O₂

Purity: ≥98%

Molecular weight: 359.81

Ref: 54-BUP10376

3-[(3-Chlorophenoxy)methyl]-1-(Tetrahydro-2h-Pyran-4-Yl)-1h-Pyrazolo[3,4-D]pyrimidin-4-Amine

CAS: 1188296-52-7

Formula: C₁₇H₁₈ClN₅O₂

Purity: 99%

Color and Shape: Solid

Molecular weight: 359.8101

Ref: IN-DA008ZG4

3-((3-Chlorophenoxy)Methyl)-1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazolo[3,4-d]Pyrimidin-4-Amine

CAS: 1188296-52-7

3-((3-Chlorophenoxy)Methyl)-1-(Tetrahydro-2H-Pyran-4-Yl)-1H-Pyrazolo[3,4-d]Pyrimidin-4-Amine

Formula: C₁₇H₁₈ClN₅O₂

Purity: 99%

Molecular weight: 359.81

Ref: 54-OR1024037

PF-4800567

CAS: 1188296-52-7

3-((3-Chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Formula: C₁₇H₁₈ClN₅O₂

Purity: 99%

Molecular weight: 359.81

Ref: IN-DG607287

PF-4800567

CAS: 1188296-52-7

PF-4800567 is a selective inhibitor of casein kinase 1ε (CK1ε; IC50 = 32 nM) with greater than 20-fold selectivity over CK1δ.

Formula: C₁₇H₁₈ClN₅O₂

Purity: 99.74% - 99.76%

Color and Shape: White Solid

Molecular weight: 359.81

Ref: TM-T5056

PF-4800567

CAS: 1188296-52-7

PF-4800567 is a small molecule that inhibits the activity of β-catenin, a protein that plays an important role in the regulation of cell growth and differentiation. This drug has been shown to have minimal toxicity in animals and has been used as a chemical biology tool for the study of β-catenin function. PF-4800567 is also being developed as a potential treatment for bladder cancer. In animal models, this drug has shown efficacy in reducing tumor size and increasing survival rates. The compound also inhibits the growth of t-cell lymphomas by blocking β-catenin signaling pathways. PF-4800567 has shown efficacy as an inhibitor of locomotor activity in mice and can be used to study metabolic disorders such as diabetes. This compound may also be useful for treating autoimmune diseases due to its ability to suppress immune responses.

Formula: C₁₇H₁₈ClN₅O₂

Purity: Min. 95%

Molecular weight: 359.81 g/mol

Ref: 3D-NXB29652