CAS 118904-37-3: FMOC-D-ALLO-ILE-OH
Description:FMOC-D-ALLO-ILE-OH, also known as 9-fluorenylmethoxycarbonyl-D-alloisoleucine, is a protected amino acid commonly used in peptide synthesis. The FMOC group serves as a temporary protective group for the amino functionality, allowing for selective reactions during the synthesis process. This compound features a unique alloisoleucine structure, which is an isomer of isoleucine, characterized by its branched-chain configuration. The presence of the FMOC group enhances the solubility of the amino acid in organic solvents, facilitating its use in various coupling reactions. FMOC-D-ALLO-ILE-OH is typically utilized in solid-phase peptide synthesis, where the protection and deprotection of functional groups are crucial for the successful assembly of peptides. Its stability under basic conditions and compatibility with various coupling reagents make it a valuable building block in the field of medicinal chemistry and peptide research. As with many amino acids, it is essential to handle this compound with care, following appropriate safety protocols to ensure safe laboratory practices.
Formula:C21H23NO4
InChI:InChI=1/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19+/m0/s1
- Synonyms:
- N-Alpha-(9-Fluorenylmethyloxycarbonyl)-D-Allo-Isoleucine
- N-Alpha-(9-Fluorenylmethoxycarbonyl)-D-Allo-Isoleucine
- Fmoc-D-Allo-Isoleucine
- D-N-Fmoc-Alloisoleucine
- (2R,3S)-N-Fmoc-2-Amino-3-Methylpentanoic Acid
- Fmoc-D-Allo-Lle-Oh
- N-Alpha-(9-Fluoroenylmethyloxycarbonyl)-D-Allo-Isoleucine
- N-[(9H-Fluoren-9-Ylmethoxy)Carbonyl]-D-Alloisoleucine
- Fmoc-D-Alloisoleucine