CAS 119-24-4
:pteroic acid
Description:
Pteroic acid, with the CAS number 119-24-4, is a naturally occurring compound that belongs to the class of pteridines. It is a yellow crystalline solid that is soluble in water and alcohol, but less so in non-polar solvents. Pteroic acid is a key component in the biosynthesis of folate, playing a crucial role in the metabolism of nucleic acids and amino acids. Its structure features a bicyclic pteridine ring system, which is essential for its biological activity. Pteroic acid is often found in various foods and is important for cellular functions, particularly in the synthesis of tetrahydrofolate, a coenzyme involved in one-carbon metabolism. In laboratory settings, it is used as a reference compound in studies related to folate metabolism and can also serve as a precursor in the synthesis of other biologically active compounds. Due to its role in human health, pteroic acid is of interest in nutritional and pharmaceutical research, particularly concerning its implications in deficiencies and related diseases.
Formula:C14H12N6O3
InChI:InChI=1S/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)
InChI key:InChIKey=JOAQINSXLLMRCV-UHFFFAOYSA-N
SMILES:O=C1C=2C(NC=C(CNC3=CC=C(C(O)=O)C=C3)N2)=NC(N)=N1
Synonyms:- 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid
- 4-{[(2-Amino-4-Oxo-1,4-Dihydropteridin-6-Yl)Methyl]Amino}Benzoic Acid
- Benzoic acid, 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-
- Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-
- Benzoic acid, p-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-
- NSC 14972
- P-((2-Amino-4-Hydroxypteridin-6-Yl)Methylamino)Benzoic Acid
- Pyrofolic acid
- p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic acid
- Pteroic acid
- 4-(((2-amino-4-hydroxypteridin-6-yl)
- Folic acid EP Impurity D
- 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
- Folic acid iMpurity D
- Folic acid impurity D CRS
- Pteroic Acid (>
- 4-[[(2-Amino-4-oxo-1,4-dihydropteri
- 4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid
- Folic Acid Impurity 6
- Methotrexate EP Impurity D N-Desmethyl Impurity
- Pteroic acid(Instant type)
- Folic Acid Impurity 6（Folic Acid EP Impurity D）
- Methotrexate EP Impurity D Desmethyl Impurity
- 4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)
- Pteroic Acid (>85%)
- 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid
- Pteroic acid - min95%
- 4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
- Pteroic acid >=93%
- PTEROIC ACID HYDRATE, 90%
- See more synonyms
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Found 12 products.
4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid
CAS:4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acidFormula:C14H12N6O3Purity:95%Color and Shape: yellow solidMolecular weight:312.28348g/mol4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzoic acid
CAS:Purity:95.0%Color and Shape:Solid, Yellow powderMolecular weight:312.289001464843754-[[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoic Acid (Pteroic Acid)
CAS:Color and Shape:NeatPTEROIC ACID
CAS:<p>Pteroic acid is part of the structure of folic acid</p>Formula:C14H12N6O3Purity:96.4% - >99.99%Color and Shape:SolidMolecular weight:312.28Pteroic Acid (>85%)
CAS:Controlled Product<p>Impurity Methotrexate EP Impurity D N-Desmethyl Impurity<br>Applications Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.<br>References Vickers, P.J. et al.: Can. J. Biochem. Cell Biol., 63, 777 (1985): Tafolla, W.H. et al.: J. Pharmac. Sci., 70, 1273 (1981); Iwai, K. et al.: J. Butrit. Sci. Vitaminol., 23, 95 (1977);<br></p>Formula:C14H12N6O3Purity:>85%Color and Shape:NeatMolecular weight:312.28Pteroic acid - 60%
CAS:<p>Pteroic acid is a synthetic compound that is an analog of the natural amino acid phenylalanine. It has been shown to inhibit protein synthesis and may be useful for the treatment of cancer. Pteroic acid can be activated by the addition of trifluoroacetic acid and reacts with metal ions such as nickel, cobalt, copper, and zinc. It also binds to receptors on tubule cells in kidney tissue. This binding inhibits the enzyme carbonic anhydrase II, which catalyzes the conversion of carbon dioxide to bicarbonate in these cells. The inhibition of this enzyme results in a decrease in bicarbonate concentration within these cells, leading to cell death.</p>Formula:C14H12N6O3Purity:Min. 93 Area-%Color and Shape:PowderMolecular weight:312.28 g/molPteroic acid, min95%
CAS:<p>Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.</p>Formula:C14H12N6O3Purity:Min. 95%Color and Shape:Slightly Yellow PowderMolecular weight:312.28 g/mol
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