CAS 119-24-4

pteroic acid

Description:

Pteroic acid, with the CAS number 119-24-4, is a naturally occurring compound that belongs to the class of pteridines. It is a yellow crystalline solid that is soluble in water and alcohol, but less so in non-polar solvents. Pteroic acid is a key component in the biosynthesis of folate, playing a crucial role in the metabolism of nucleic acids and amino acids. Its structure features a bicyclic pteridine ring system, which is essential for its biological activity. Pteroic acid is often found in various foods and is important for cellular functions, particularly in the synthesis of tetrahydrofolate, a coenzyme involved in one-carbon metabolism. In laboratory settings, it is used as a reference compound in studies related to folate metabolism and can also serve as a precursor in the synthesis of other biologically active compounds. Due to its role in human health, pteroic acid is of interest in nutritional and pharmaceutical research, particularly concerning its implications in deficiencies and related diseases.

Formula: C₁₄H₁₂N₆O₃

InChI: InChI=1S/C14H12N6O3/c15-14-19-11-10(12(21)20-14)18-9(6-17-11)5-16-8-3-1-7(2-4-8)13(22)23/h1-4,6,16H,5H2,(H,22,23)(H3,15,17,19,20,21)

InChI key: InChIKey=JOAQINSXLLMRCV-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC=C(CNC3=CC=C(C(O)=O)C=C3)N2)=NC(N)=N1

Synonyms:

• 4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic acid
• 4-{[(2-Amino-4-Oxo-1,4-Dihydropteridin-6-Yl)Methyl]Amino}Benzoic Acid
• Benzoic acid, 4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-
• Benzoic acid, 4-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-
• Benzoic acid, p-[[(2-amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]-
• NSC 14972
• P-((2-Amino-4-Hydroxypteridin-6-Yl)Methylamino)Benzoic Acid
• Pyrofolic acid
• p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic acid
• Pteroic acid
• 4-(((2-amino-4-hydroxypteridin-6-yl)
• Folic acid EP Impurity D
• 4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
• Folic acid iMpurity D
• Folic acid impurity D CRS
• Pteroic Acid (&gt
• 4-[[(2-Amino-4-oxo-1,4-dihydropteri
• 4-[(2-amino-4-keto-1H-pteridin-6-yl)methylamino]benzoic acid
• Folic Acid Impurity 6
• Methotrexate EP Impurity D N-Desmethyl Impurity
• Pteroic acid(Instant type)
• Folic Acid Impurity 6（Folic Acid EP Impurity D）
• Methotrexate EP Impurity D Desmethyl Impurity
• 4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)
• Pteroic Acid (>85%)
• 4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid
• Pteroic acid - min95%
• 4-[(2-azanyl-4-oxo-1H-pteridin-6-yl)methylamino]benzoic acid
• Pteroic acid >=93%
• PTEROIC ACID HYDRATE, 90%

FOLIC ACID IMPURITY D CRS

CAS: 119-24-4

FOLIC ACID IMPURITY D CRS

Ref: 41-Y0001243

Pteroic acid

CAS: 119-24-4

Formula: C₁₄H₁₂N₆O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 312.2835

Ref: IN-DA003JXC

4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid

CAS: 119-24-4

4-{[(2-Amino-4-hydroxypteridin-6-yl)methyl]amino}benzoic acid

Formula: C₁₄H₁₂N₆O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 312.28348

Ref: 54-OR17919

PTEROIC ACID

CAS: 119-24-4

PTEROIC ACID

Formula: C₁₄H₁₂N₆O₃

Purity: ≥95%

Molecular weight: 312.28

Ref: 54-BUP16501

4-[[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino]benzoic Acid (Pteroic Acid)

CAS: 119-24-4

Color and Shape: Neat

Ref: 86-MM0621.04

4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzoic acid

CAS: 119-24-4

Purity: 95.0%

Color and Shape: Solid, Yellow powder

Molecular weight: 312.28900146484375

Ref: 10-F319353

Folic Acid EP Impurity D

CAS: 119-24-4

Formula: C₁₄H₁₂N₆O₃

Color and Shape: Yellow Solid

Molecular weight: 312.29

Ref: 4Z-F-2426

Folic Acid Impurity D

CAS: 119-24-4

4-(((2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)amino)benzoic acid

Formula: C₁₄H₁₂N₆O₃

Purity: 95%

Molecular weight: 312.28

Ref: IN-DG149448

PTEROIC ACID

CAS: 119-24-4

Pteroic acid is part of the structure of folic acid

Formula: C₁₄H₁₂N₆O₃

Purity: 96.4% - >99.99%

Color and Shape: Solid

Molecular weight: 312.28

Ref: TM-T8854

Folic acid EP Impurity D

CAS: 119-24-4

Formula: C₁₄H₁₂N₆O₃

Molecular weight: 312.28

Ref: ST-EA-CP-F5004

Pteroic Acid (>85%)

Controlled Product

CAS: 119-24-4

Impurity Methotrexate EP Impurity D N-Desmethyl Impurity
Applications Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.
References Vickers, P.J. et al.: Can. J. Biochem. Cell Biol., 63, 777 (1985): Tafolla, W.H. et al.: J. Pharmac. Sci., 70, 1273 (1981); Iwai, K. et al.: J. Butrit. Sci. Vitaminol., 23, 95 (1977);

Formula: C₁₄H₁₂N₆O₃

Purity: >85%

Color and Shape: Neat

Molecular weight: 312.28

Ref: TR-P840110

Pteroic acid - 60%

CAS: 119-24-4

Pteroic acid is a synthetic compound that is an analog of the natural amino acid phenylalanine. It has been shown to inhibit protein synthesis and may be useful for the treatment of cancer. Pteroic acid can be activated by the addition of trifluoroacetic acid and reacts with metal ions such as nickel, cobalt, copper, and zinc. It also binds to receptors on tubule cells in kidney tissue. This binding inhibits the enzyme carbonic anhydrase II, which catalyzes the conversion of carbon dioxide to bicarbonate in these cells. The inhibition of this enzyme results in a decrease in bicarbonate concentration within these cells, leading to cell death.

Formula: C₁₄H₁₂N₆O₃

Purity: Min. 93 Area-%

Color and Shape: Powder

Molecular weight: 312.28 g/mol

Ref: 3D-IP35440

Pteroic acid, min95%

CAS: 119-24-4

Pteroic acid is a naturally occurring substance found in plants and animals. It has inhibitory activities against enzymes such as butyrate kinase, acetyl-CoA synthetase, and glutamate dehydrogenase. Pteroic acid is used to synthesize quinoxalines, which are used for the treatment of cancer. Pteroic acid also inhibits cell growth by inhibiting protein synthesis. This is done by conjugating with amino acids and inhibiting their uptake into the ribosome. The inhibition of glutamate dehydrogenase may be due to its ability to reduce levels of glutathione, which is an inhibitor of this enzyme.

Formula: C₁₄H₁₂N₆O₃

Purity: Min. 95%

Color and Shape: Slightly Yellow Powder

Molecular weight: 312.28 g/mol

Ref: 3D-IP163598