CAS 1190836-34-0

Formula: C27H23FN4O4S

InChI: InChI=1S/C27H23FN4O4S/c1-29-26(34)19-14-18-21(15-24(19)35-2)30-11-10-22(18)36-23-9-8-17(13-20(23)28)31-27(37)32-25(33)12-16-6-4-3-5-7-16/h3-11,13-15H,12H2,1-2H3,(H,29,34)(H2,31,32,33,37)

InChI key: ORRNXRYWGDUDOG-UHFFFAOYSA-N

SMILES: CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=C(C=C(C=C3)NC(=S)NC(=O)CC4=CC=CC=C4)F

Pamufetinib

CAS: 1190836-34-0

Pamufetinib (TAS-115) is a potent inhibitor of VEGFR and hepatocyte growth factor receptor (c-Met/HGFR)-targeted kinase.

Formula: C₂₇H₂₃FN₄O₄S

Purity: 99.39%

Color and Shape: White Solid

Molecular weight: 518.559

Ref: TM-T13108

Pamufetinib

CAS: 1190836-34-0

Pamufetinib

Formula: C₂₇H₂₃FN₄O₄S

Purity: 99%

Molecular weight: 518.56

Ref: 54-BUP08873

4-[2-Fluoro-4-[[[(2-phenylacetyl)amino]thioxomethyl]amino]phenoxy]-7-methoxy-N-methyl-6-quinolinecarboxamide

CAS: 1190836-34-0

Purity: 98%

Ref: IN-DA01EO7F

Pamufetinib

CAS: 1190836-34-0

4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide

Formula: C₂₇H₂₃FN₄O₄S

Purity: 99%

Molecular weight: 518.56

Ref: IN-DG01114101

TAS-115

CAS: 1190836-34-0

TAS-115 is a monoclonal antibody that binds to the epidermal growth factor receptor (EGFR) and blocks the EGFR signalling pathway. It is used in the treatment of solid tumours, such as lung cancer. TAS-115 has been shown to inhibit Wnt signalling by interfering with the binding of kinase domain of EGFR to its substrate, which leads to inhibition of proliferation and induction of apoptosis in human osteosarcoma cells. In addition, TAS-115 was found to be a potential biomarker for colon cancer.

Formula: C₂₇H₂₃FN₄O₄S

Purity: Min. 95%

Molecular weight: 518.6 g/mol

Ref: 3D-QXB83634