CAS: 1195768-06-9 - dabrafenib mesylate

Formula: C₂₃H₂₀F₃N₅O₂S₂.CH₄O₃S

InChI: InChI=1S/C23H20F3N5O2S2.CH4O3S/c1-23(2,3)21-30-18(19(34-21)16-10-11-28-22(27)29-16)12-6-4-9-15(17(12)26)31-35(32,33)20-13(24)7-5-8-14(20)25;1-5(2,3)4/h4-11,31H,1-3H3,(H2,27,28,29);1H3,(H,2,3,4)

InChI key: InChIKey=YKGMKSIHIVVYKY-UHFFFAOYSA-N

SMILES: O=S(=O)(O)C.O=S(=O)(NC=1C=CC=C(C1F)C=2N=C(SC2C=3N=C(N=CC3)N)C(C)(C)C)C=4C(F)=CC=CC4F

Benzenesulfonamide, N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-, methanesulfonate (1:1)

CAS: 1195768-06-9

• Formula: C₂₄H₂₄F₃N₅O₅S₃
• Purity: ≥98%(HPLC)
• Color and Shape: Solid
• Molecular weight: 615.6681

Dabrafenib Mesilate

CAS: 1195768-06-9

• Color and Shape: Neat

Dabrafenib Mesylate

CAS: 1195768-06-9

• Formula: C₂₃H₂₀F₃N₅O₂S₂·CH₄O₃S
• Molecular weight: 519.56. 96.10

Dabrafenib Mesylate

CAS: 1195768-06-9

Dabrafenib Mesylate (GSK2118436 Mesylate) is a B-Raf inhibitor(IC50s of 0.6 and 5.0 nM for RafV600E …

• Formula: C₂₄H₂₄F₃N₅O₅S₃
• Purity: 99.45%
• Color and Shape: Solid
• Molecular weight: 615.67

Dabrafenib mesylate

CAS: 1195768-06-9

Inhibitor of B-Raf kinase mutant

• Formula: C₂₃H₂₀F₃N₅O₂S₂·CH₄O₃S
• Purity: Min. 95%
• Color and Shape: White/Off-White Solid
• Molecular weight: 615.67

Dabrafenib Mesylate

CAS: 1195768-06-9

Stability Hygroscopic Applications Dabrafenib is an inhibitor of mutated BRAF kinase and has clinical activity …

• Formula: C₂₄H₂₄F₃N₅O₅S₃
• Color and Shape: White
• Molecular weight: 615.67

Dabrafenib Mesylate

CAS: 1195768-06-9

• Formula: C₂₃H₂₀F₃N₅O₂S₂·CH₃SO₃H
• Purity: 99.99% (Typical Value in Batch COA)
• Color and Shape: white solid
• Molecular weight: 615.67g/mol