CAS 1196541-47-5

Formula: C16H20BrN5O

InChI: InChI=1S/C16H20BrN5O/c17-11-6-19-15-13(14(11)22-5-1-2-10(18)8-22)12(7-20-15)21-16(23)9-3-4-9/h6-7,9-10H,1-5,8,18H2,(H,19,20)(H,21,23)/t10-/m1/s1

InChI key: BAZRWWGASYWYGB-SNVBAGLBSA-N

SMILES: C1C[C@H](CN(C1)C2=C3C(=CNC3=NC=C2Br)NC(=O)C4CC4)N

GDC-0575

CAS: 1196541-47-5

GDC-0575

Formula: C₁₆H₂₀BrN₅O

Purity: ≥95%

Molecular weight: 378.27

Ref: 54-BUP03612

GDC-0575

CAS: 1196541-47-5

Formula: C₁₆H₂₀BrN₅O

Purity: %

Color and Shape: Solid

Molecular weight: 378.2669

Ref: IN-DA01EOPK

(R)-N-(4-(3-Aminopiperidin-1-Yl)-5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Cyclopropanecarboxamide

CAS: 1196541-47-5

(R)-N-(4-(3-Aminopiperidin-1-Yl)-5-Bromo-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)Cyclopropanecarboxamide

Formula: C₁₆H₂₀BrN₅O

Purity: 98+%

Molecular weight: 378.27

Ref: 54-OR1024361

GDC-0575

CAS: 1196541-47-5

GDC-0575 (ARRY-575) is a highly-selective oral small-molecule Chk1 inhibitor(IC50 of 1.2 nM).

Formula: C₁₆H₂₀BrN₅O

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 378.267

Ref: TM-T7300

GDC-0575

CAS: 1196541-47-5

(R)-N-(4-(3-Aminopiperidin-1-yl)-5-bromo-1H-pyrrolo[2,3-b]pyridin-3-yl)cyclopropanecarboxamide

Formula: C₁₆H₂₀BrN₅O

Purity: 98+%

Molecular weight: 378.27

Ref: IN-DG760270

GDC-0575

CAS: 1196541-47-5

Purity: 98+%

Molecular weight: 377.085

Ref: 10-F859434

GDC-0575

CAS: 1196541-47-5

GDC-0575 is a small molecule inhibitor that specifically targets the Ataxia-Telangiectasia and Rad3-related protein (ATR) kinase. This compound, developed from a synthetic chemical source, functions by selectively inhibiting the ATR kinase, a key regulator of the DNA damage response pathway. By binding to the active site of ATR, GDC-0575 disrupts its ability to activate downstream effectors involved in DNA repair processes.

Formula: C₁₆H₂₀BrN₅O

Purity: Min. 95%

Molecular weight: 378.27 g/mol

Ref: 3D-WXB54147