CAS 1197-18-8
:tranexamic acid
Description:
Tranexamic acid is a synthetic amino acid derivative, primarily recognized for its antifibrinolytic properties, which inhibit the breakdown of fibrin in blood clots. This compound is often utilized in medical settings to manage excessive bleeding, particularly in conditions such as heavy menstrual bleeding, surgical procedures, and trauma. Chemically, tranexamic acid is characterized by its ability to bind to lysine residues on plasminogen, thereby preventing its conversion to plasmin, the enzyme responsible for fibrinolysis. The substance is typically administered orally or intravenously and is known for its relatively low toxicity profile. In terms of physical properties, tranexamic acid is a white crystalline powder that is soluble in water and exhibits a neutral pH in solution. Its molecular structure includes a cyclohexane ring, contributing to its stability and efficacy. Overall, tranexamic acid is a vital therapeutic agent in the management of bleeding disorders, with ongoing research exploring its potential applications in various medical fields.
Formula:C8H15NO2
InChI:InChI=1/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)/t6-,7-
InChI key:InChIKey=GYDJEQRTZSCIOI-LJGSYFOKNA-N
SMILES:C(O)(=O)[C@H]1CC[C@H](CN)CC1
Synonyms:- 4-(Aminomethyl)Cyclohexanecarboxylic Acid
- 4-trans-Aminomethylcyclohexanecarboxylic acid
- Acide Tranexamique
- Acido Tranexamico
- Amca
- Amcha
- Amchafibrin
- Amikapron
- Amstat
- Anvitoff
- Bay 3517
- Cl 65336
- Cyclocapron
- Cyclohexanecarboxylic acid, 4-(aminomethyl)-, trans-
- Cyclokapron
- Cyklokapron
- Dv 79
- Exacyl
- Haematrix
- Haku
- Lysteda
- Tamcha
- Tranexaminsaure
- Tranol
- Trans-4-aminomethylcyclohexanecarboxylic acid
- Trans-Cyclohexanecarboxylic Acid
- Transamin
- Transamin G
- Transamin S
- Transcam
- Ugurol
- Xamig
- Xed
- Zataranax
- t-AMCHA
- trans-4-(Aminomethyl)-1-cyclohexanecarboxylic acid
- trans-4-(Aminomethyl)cyclohexane carboxylic acid
- trans-4-(Aminomethyl)cyclohexanecarboxylic acid
- trans-4-Aminomethylcyclohexane-1-carboxylate
- trans-Amcha
- trans-Tranexamic acid
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
trans-4-(Aminomethyl)cyclohexanecarboxylic acid, 97%
CAS:It is an antifibrinolytic agent that is found to inhibit plasmin-induced fibrinolysis. Used in various hemorrhagic diseases , abnormal bleeding in operations. It is also used as a lysine analogue to characterize binding sites in plasminogen. This Thermo Scientific Chemicals brand product was originaFormula:C8H15NO2Purity:97%Color and Shape:White, Crystals or powder or crystalline powderMolecular weight:157.21Tranexamic acid
CAS:Tranexamic acidFormula:C8H15NO2Purity:99.5%Color and Shape:White. To. Off-WhiteMolecular weight:157.11028Tranexamic Acid
CAS:Amino-acids (excluding aromatic) and their esters other than those containing more than one kind of oxygen function, nesoiFormula:C8H15NO2Color and Shape:White Beige Crystalline PowderMolecular weight:157.11028trans-4-(Aminomethyl)cyclohexanecarboxylic acid
CAS:trans-4-(Aminomethyl)cyclohexanecarboxylic acidFormula:C8H15NO2Purity:98%Color and Shape:Solid-PowderMolecular weight:157.2102Tranexamic acid
CAS:Tranexamic acid (Amstat) is an Antifibrinolytic Agent. The physiologic effect of tranexamic acid is by means of Decreased Fibrinolysis.Formula:C8H15NO2Purity:99.64% - 99.79%Color and Shape:White Crystalline PowderMolecular weight:157.21(1r,4r)-4-(aminomethyl)cyclohexane-1-carboxylic acid
CAS:Formula:C8H15NO2Purity:95%Color and Shape:SolidMolecular weight:157.2102Tranexamic acid
CAS:Formula:C8H15NO2Purity:(Titration) 99.0 - 101.0 % (dried basis)Color and Shape:White or almost white crystalline powderMolecular weight:157.21Tranexamic Acid
CAS:Controlled ProductFormula:C8H15NO2Color and Shape:White To Off-WhiteMolecular weight:157.21Tranexamic acid 100 µg/mL in Acetonitrile:Water
CAS:Formula:C8H15NO2Color and Shape:Single SolutionMolecular weight:157.21trans-4-(Aminomethyl)cyclohexanecarboxylic Acid
CAS:Formula:C8H15NO2Purity:>98.0%(GC)(T)Color and Shape:White to Almost white powder to crystalMolecular weight:157.21Tranexamic Acid
CAS:Controlled ProductStability Hygroscopic
Applications Antifibrinolytic agent; blocks lysine binding sites of plasminogen. Hemostatic.
References Andersson, et al.: Scand. J. Haematol. 2, 230 (1965), Melander, B., et al.: Acta Pharmacol. Toxicol., 22, 340 (1965), Bonnar, J., et al.: Br. Med. J., 313, 579 (1996), Dunn, C.J., et al.: Drugs, 57, 1005 (1999),Formula:C8H15NO2Color and Shape:NeatMolecular weight:157.21trans-Tranexamic acid
CAS:Trans-tranexamic acid is a drug that has been used in cardiac surgery and to control blood loss during childbirth. It is also used to treat people with bowel disease who have heavy or prolonged bleeding. Trans-tranexamic acid works by inhibiting the activity of plasminogen activators, which are enzymes that break down fibrin clots. Tranexamic acid has been shown to be effective for treating people with severe sepsis and meningitis, although it does not appear to be effective for treating malaria. Trans-tranexamic acid binds to plasminogen activator inhibitor type 1 (PAI-1), preventing its activation and, therefore, preventing the breakdown of fibrin clots. Tranexamic acid also prevents the release of histamine from mast cells and basophils, which may contribute to its anti-inflammatory effects.Formula:C8H15NO2Purity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:157.21 g/moltrans-4-(Aminomethyl)cyclohexanecarboxylic acid
CAS:Formula:C8H15NO2Purity:95%Color and Shape:Crystalline Powder,PowderMolecular weight:157.11
