CAS 120011-70-3
:Donepezil hydrochloride
Description:
Donepezil hydrochloride is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of Alzheimer's disease and other cognitive disorders. It enhances cholinergic function by increasing the levels of acetylcholine in the brain, which is crucial for memory and learning. The compound is typically administered in its hydrochloride salt form, which improves its solubility and bioavailability. Donepezil hydrochloride is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, and it has a specific molecular weight. The substance is usually presented as a white to off-white crystalline powder, and it is soluble in water and alcohol. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for once-daily dosing. Common side effects may include gastrointestinal disturbances, insomnia, and muscle cramps. As with any medication, it is essential to use Donepezil hydrochloride under medical supervision to monitor for efficacy and potential adverse reactions.
Formula:C24H30ClNO3
InChI:InChI=1/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H
InChI key:InChIKey=XWAIAVWHZJNZQQ-UHFFFAOYSA-N
SMILES:O=C1C=2C(=CC(OC)=C(OC)C2)CC1CC3CCN(CC4=CC=CC=C4)CC3.Cl
Synonyms:- 1-Benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride
- 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride
- 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)
- 2,3-Dihydro-5,6-Dimethoxy-2-[[1-(Phenylmethyl)-4-Piperidinyl]Methyl]-1H-Inden-1-One Hydrochloride
- 2,3-dihydro-5,6-dimethoxy-2-{[1-(phemylmethyl)-4-piperidinyl]methyl}-1H-indan-1-one HCL
- 2-(1-Benzylpiperidin-4-ylmethyl)-5,6-dimethoxyindan-1-one hydrochloride
- 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride (1:1)
- Akos 226-31
- Aricept
- Aricept D
- Aricept ODT
- Aricept, E-2020 Donepezil HCl
- Donep
- Donepezil HCl
- DonepezilHCL
- DonepezilHcl120011-70-3
- Donezepil hydrochloride
- Dopezil
- Dorent
- E 2020 (pharmaceutical)
- E-2020
- BNAG
- 1h-inden-1-one,2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)me
- e2020(pharmaceutical)
- Donepezi
- DONEPEZIL HYDROCHLORIDE
- Aricept, E-2020
- 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]-1H-inden-1-one
- Donepezil and its intermediates
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 18 products.
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)
CAS:Formula:C24H30ClNO3Purity:98%Color and Shape:SolidMolecular weight:415.9529Ref: IN-DA000Q2S
1g25.00€5g43.00€10g60.00€1kgTo inquire25g105.00€50gTo inquire5kgTo inquire100g231.00€250gTo inquire500gTo inquire100mgTo inquire2-((1-Benzylpiperidin-4-Yl)Methyl)-5,6-Dimethoxy-2,3-Dihydro-1H-Inden-1-One Hydrochloride
CAS:2-((1-Benzylpiperidin-4-Yl)Methyl)-5,6-Dimethoxy-2,3-Dihydro-1H-Inden-1-One HydrochloridePurity:98%Molecular weight:415.95g/molDonepezil-d5 HCl
CAS:Formula:C24H24D5NO3·HClColor and Shape:White To Off-White SolidMolecular weight:384.53 36.46Donepezil Hydrochloride
CAS:Formula:C24H29NO3·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:415.96Donepezil Hydrochloride
CAS:<p>Donepezil HCl(Aricept) is a selective and effective AChE inhibitor for bAChE and hAChE (IC50: 8.12/11.6 nM).</p>Formula:C24H29NO3·HClPurity:99.55% - 99.8%Color and Shape:White To Off-White Crystalline SolidMolecular weight:415.96Donepezil hydrochloride
CAS:Formula:C24H29NO3·HCl·H2OPurity:≥ 98.0%Color and Shape:White to off-white crystalline powderMolecular weight:415.95 (anhydrous)Donepezil Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications A nootropic. An inhibitor of acetylcholinesterase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ohnishi, A., et al.: J. Clin. Pharmacol., 33, 1086 (1993); Galli, A., et al.: Eur. J. Pharmacol., 270, 189 (1994);<br></p>Formula:C24H29NO3·ClHColor and Shape:White To Off-WhiteMolecular weight:415.95Donepezil HCl
CAS:Controlled Product<p>Reversible inhibitor of cholinesterases</p>Formula:C24H29NO3·HClPurity:Min. 98 Area-%Color and Shape:White PowderMolecular weight:415.95 g/molDonepezil HCl - Bio-X ™
CAS:Controlled Product<p>Donepezil HCl is a reversible inhibitor of acetylcholinesterase (AChE), a type of cholinesterase enzyme. Donepezil HCl temporarily binds to and blocks the active site of the enzyme, inhibiting the enzyme's ability to break down acetylcholine, a neurotransmitter involved in learning and memory. This increase in acetylcholine concentrations at cholinergic synapses helps improve cognitive function in patients with Alzheimer's disease. Donepezil HCl may also have a role in calcium signalling through interaction with sigma receptors in the endoplasmic reticulum (ER).</p>Formula:C24H30ClNO3Purity:Min. 99 Area-%Color and Shape:Off-White PowderMolecular weight:415.95 g/molDonepezil hydrochloride
CAS:Controlled ProductFormula:C24H29NO3·ClHColor and Shape:NeatMolecular weight:415.95
![1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochlori…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA000Q2S.jpg&w=3840&q=75)
