CAS 120011-70-3: Donepezil hydrochloride

Description:Donepezil hydrochloride is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of Alzheimer's disease and other cognitive disorders. It enhances cholinergic function by increasing the levels of acetylcholine in the brain, which is crucial for memory and learning. The compound is typically administered in its hydrochloride salt form, which improves its solubility and bioavailability. Donepezil hydrochloride is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, and it has a specific molecular weight. The substance is usually presented as a white to off-white crystalline powder, and it is soluble in water and alcohol. Its pharmacokinetics indicate that it has a relatively long half-life, allowing for once-daily dosing. Common side effects may include gastrointestinal disturbances, insomnia, and muscle cramps. As with any medication, it is essential to use Donepezil hydrochloride under medical supervision to monitor for efficacy and potential adverse reactions.

Formula:C₂₄H₂₉NO₃·ClH

InChI:InChI=1S/C24H29NO3.ClH/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1H

InChI key:InChIKey=XWAIAVWHZJNZQQ-UHFFFAOYSA-N

SMILES:Cl.O=C1C2=CC(OC)=C(OC)C=C2CC1CC3CCN(CC=4C=CC=CC4)CC3

Synonyms:
1-Benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1)
2,3-Dihydro-5,6-Dimethoxy-2-[[1-(Phenylmethyl)-4-Piperidinyl]Methyl]-1H-Inden-1-One Hydrochloride
2,3-dihydro-5,6-dimethoxy-2-{[1-(phemylmethyl)-4-piperidinyl]methyl}-1H-indan-1-one HCL
2-(1-Benzylpiperidin-4-ylmethyl)-5,6-dimethoxyindan-1-one hydrochloride
2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one hydrochloride (1:1)
Akos 226-31
Aricept
Aricept D
See more synonyms
Aricept ODT
Aricept, E-2020 Donepezil HCl
Donep
Donepezil HCl
DonepezilHCL
DonepezilHcl120011-70-3
Donezepil hydrochloride
Dopezil
Dorent
E 2020 (pharmaceutical)
E-2020
BNAG

Found 15 products.

Product data	Purity	Price range	Estimated delivery
Donepezil Hydrochloride REF: 3B-D4099CAS: 120011-70-3 120014-06-4	>98.0%(T)(HPLC)	62.00 €~181.00 €	Thu 20 Mar 25
Donepezil hydrochloride CRS REF: 41-Y0002160CAS: 120011-70-3	- - -	115.00 €	Tue 25 Mar 25
1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-, hydrochloride (1:1) REF: IN-DA000Q2SCAS: 120011-70-3	98%	To inquire	Thu 27 Mar 25
Donepezil-d5 HCl REF: 4Z-D-1329CAS: 120011-70-3	- - -	745.00 €~5,178.00 €	Fri 28 Mar 25
2-((1-Benzylpiperidin-4-Yl)Methyl)-5,6-Dimethoxy-2,3-Dihydro-1H-Inden-1-One Hydrochloride REF: 54-OR1009606CAS: 120011-70-3	98%	32.00 €~1,226.00 €	Fri 28 Mar 25
Donepezil Hydrochloride REF: 86-MM0677.00-0250CAS: 120011-70-3	- - -	3,631.00 €	Tue 01 Apr 25
Donepezil hydrochloride REF: AC-45805CAS: 120011-70-3	- - -	68.00 €~225.00 €	Tue 01 Apr 25
Donepezil hydrochloride REF: 04-C13081750CAS: 120011-70-3	- - -	To inquire	Tue 01 Apr 25
Donepezil hydrochloride REF: 7W-GP8656CAS: 120011-70-3	≥ 98.0%	341.00 €	Thu 03 Apr 25
Donepezil Hydrochloride REF: TM-T6478CAS: 120011-70-3	99.55% - 99.8%	52.00 €~205.00 €	Thu 03 Apr 25
Donepezil Hydrochloride RS REF: 2K-1090500021CAS: 120011-70-3	- - -	To inquire	Fri 04 Apr 25
Donepezil Hydrochloride REF: TR-D531750CAS: 120011-70-3	- - -	150.00 €~412.00 €	Tue 08 Apr 25
Donepezil hydrochloride REF: 10-F036568CAS: 120011-70-3	99.00%	To inquire	Tue 08 Apr 25
Donepezil HCl REF: 3D-FD29053CAS: 120011-70-3	Min. 98 Area-%	136.00 €~7,765.00 €	Mon 07 Apr 25
Donepezil HCl - Bio-X ™ REF: 3D-BD164380CAS: 120011-70-3	Min. 99 Area-%	145.00 €	Mon 07 Apr 25