CAS 120014-06-4

Donepezil

Description:

Donepezil is a reversible inhibitor of the enzyme acetylcholinesterase, primarily used in the treatment of Alzheimer's disease and other cognitive disorders. Its chemical formula is C24H29NO3, and it features a piperidine ring, which is crucial for its pharmacological activity. Donepezil enhances cholinergic function by increasing the levels of acetylcholine in the brain, thereby improving cognitive function and memory in patients with Alzheimer's. The substance is typically administered orally and is known for its relatively good bioavailability and moderate half-life, allowing for once-daily dosing. Donepezil is generally well-tolerated, though it may cause side effects such as nausea, diarrhea, insomnia, and muscle cramps. Its mechanism of action and therapeutic effects make it a significant compound in the management of neurodegenerative diseases, contributing to the symptomatic relief of cognitive decline. As with any medication, it is essential for patients to consult healthcare professionals for appropriate use and monitoring.

Formula: C₂₄H₂₉NO₃

InChI: InChI=1/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3

InChI key: InChIKey=ADEBPBSSDYVVLD-UHFFFAOYSA-N

SMILES: O=C1C=2C(=CC(OC)=C(OC)C2)CC1CC3CCN(CC4=CC=CC=C4)CC3

Synonyms:

• (±)-E 2020
• 1-Benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl]methylpiperidine
• 1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine
• 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-
• 2,3-Dihydro-5,6-dimethoxy-2-[[1-(phenylmethyl)-4-piperidinyl]methyl]-1H-inden-1-one
• 2-(1-Benzyl-piperidin-4-ylmethyl)-5,6-dimethoxy-indan-1-one
• 2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
• 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
• 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one
• Donepesil
• Donepezil base
• Neuripezil
• Tonizep
• Donepezil
• 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL) METHYL] PIPERIDINE
• n-1-one
• 2,3-dihydro-5,6-dimethoxy-2-((1-(phenylmethyl)-4-piperidinyl)methyl)-1h-inde
• Donezepil
• AKOS 226-23
• N-Benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl] piperidine

Donepezil

CAS: 120014-06-4

Color and Shape: Neat

Ref: 61-FOR0677.01

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

CAS: 120014-06-4

Formula: C₂₄H₂₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 379.4920

Ref: IN-DA000Q3N

Donepezil

CAS: 120014-06-4

Formula: C₂₄H₂₉NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 379.50

Ref: 4Z-D-132

Donepezil-d4 HCl

CAS: 120014-06-4

Formula: C₂₄H₂₅NO₃D₄·HCl

Molecular weight: 383.53 36.46

Ref: 4Z-D-131

Donepezil

CAS: 120014-06-4

Donepezil

Purity: ≥98%

Molecular weight: 379.49g/mol

Ref: 54-BUP13374

Donepezil Hydrochloride

CAS: 120011-70-3, 120014-06-4

Formula: C₂₄H₂₉NO₃·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 415.96

Ref: 3B-D4099

Donepezil

CAS: 120014-06-4

Donepezil (Aricept) is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE).

Formula: C₂₄H₂₉NO₃

Purity: 99.69%

Color and Shape: White Or Almost White Crystal Powder

Molecular weight: 379.49

Ref: TM-T7041

Donepezil

Controlled Product

CAS: 120014-06-4

Applications Donepezil is a cholinesterase inhibitors.
References Gawel, K., et al.: J. Psychopharmacol., 30, 676 (2016)

Formula: C₂₄H₂₉NO₃

Color and Shape: White

Molecular weight: 379.49

Ref: TR-D525745

2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

CAS: 120014-06-4

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 379.5

Ref: 10-F079408

2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one

Controlled Product

CAS: 120014-06-4

Please enquire for more information about 2-[(1-Benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₄H₂₉NO₃

Purity: Min. 95%

Molecular weight: 379.5 g/mol

Ref: 3D-VEA01406