CAS 120166-69-0

diacylglycerol kinase inhibitor ii

Description:

Diacylglycerol kinase inhibitor II, with the CAS number 120166-69-0, is a chemical compound known for its role in inhibiting diacylglycerol kinase (DGK), an enzyme involved in lipid signaling pathways. This inhibitor is often utilized in biochemical research to study the effects of DGK modulation on cellular processes, particularly in relation to signal transduction and lipid metabolism. The compound typically exhibits a specific binding affinity for the DGK enzyme, thereby preventing the conversion of diacylglycerol to phosphatidic acid, which can influence various cellular functions, including proliferation, differentiation, and apoptosis. Its chemical structure includes functional groups that facilitate interaction with the enzyme's active site. As a research tool, diacylglycerol kinase inhibitor II is valuable for exploring the physiological roles of diacylglycerol and its derivatives in various biological contexts, including cancer and cardiovascular diseases. Safety and handling precautions should be observed when working with this compound, as with any chemical substance used in laboratory settings.

Formula: C₂₈H₂₅F₂N₃OS

InChI: InChI=1/C28H25F2N3OS/c29-22-9-5-19(6-10-22)26(20-7-11-23(30)12-8-20)21-13-15-32(16-14-21)17-18-33-27(34)24-3-1-2-4-25(24)31-28(33)35/h1-12H,13-18H2,(H,31,35)

InChI key: ZCNBZFRECRPCKU-UHFFFAOYSA-N

SMILES: c1ccc2c(c1)c(=O)n(CCN1CCC(=C(c3ccc(cc3)F)c3ccc(cc3)F)CC1)c(n2)S

R59949

CAS: 120166-69-0

R59949

Formula: C₂₈H₂₅F₂N₃OS

Purity: 97%

Molecular weight: 489.58

Ref: 54-BUP12319

Diacylglycerol Kinase Inhibitor II

CAS: 120166-69-0

Formula: C₂₈H₂₅F₂N₃OS

Molecular weight: 489.58

Ref: 7W-GK5713

3-(2-(4-(Bis(4-fluorophenyl)methylene)piperidin-1-yl)ethyl)-2-thioxo-2,3-dihydroquinazolin-4(1H)-one

CAS: 120166-69-0

Formula: C₂₈H₂₅F₂N₃OS

Purity: 95%

Color and Shape: Solid

Molecular weight: 489.5794

Ref: IN-DA000QGF

R59949

CAS: 120166-69-0

R59949 is used as a Diacylglycerol kinase (DGK) inhibitor.

Formula: C₂₈H₂₅F₂N₃OS

Purity: 97.04%

Color and Shape: Solid

Molecular weight: 489.579

Ref: TM-T26019

Diacylglycerol kinase inhibitor II

CAS: 120166-69-0

Diacylglycerol kinase inhibitor II is a transcriptional regulator that inhibits diacylglycerol kinase. This inhibitor blocks the signaling pathways for growth factor-β1 by inhibiting the enzyme phosphatidic acid phosphatase, which plays an important role in cellular proliferation and migration. Diacylglycerol Kinase Inhibitor II has also been shown to inhibit cation channels and calcium release from intracellular stores. Diacylglycerol Kinase Inhibitor II binds to both cytosolic and nuclear proteins. It has been shown to inhibit cell proliferation and induce apoptosis in breast cancer cells.

Formula: C₂₈H₂₅F₂N₃OS

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 489.58 g/mol

Ref: 3D-FB102452

Diacylglycerol Kinase Inhibitor II

Controlled Product

CAS: 120166-69-0

Formula: C₂₈H₂₅F₂N₃OS

Color and Shape: Neat

Molecular weight: 489.579

Ref: TR-D110055