CAS 120202-66-6: Clopidogrel hydrogen sulfate
Description:Clopidogrel hydrogen sulfate is a pharmaceutical compound primarily used as an antiplatelet agent to prevent blood clots in patients at risk of cardiovascular events. It is a prodrug that requires metabolic activation in the liver to exert its therapeutic effects. The substance is characterized by its ability to irreversibly inhibit the P2Y12 receptor on platelets, thereby reducing platelet aggregation. Clopidogrel hydrogen sulfate is typically administered orally and is known for its relatively high bioavailability and long half-life, allowing for once-daily dosing. The compound is soluble in water and exhibits stability under normal storage conditions, although it should be protected from light and moisture. Common side effects may include bleeding complications, gastrointestinal disturbances, and hypersensitivity reactions. Due to its mechanism of action, it is often prescribed in conjunction with other antiplatelet or anticoagulant therapies, particularly in patients with a history of myocardial infarction or stroke. Monitoring for efficacy and adverse effects is essential during treatment.
Formula:C15H18ClNO6S2
InChI:InChI=1S/C16H16ClNO2S.H2O4S/c1-20-16(19)15(12-4-2-3-5-13(12)17)18-8-6-14-11(10-18)7-9-21-14;1-5(2,3)4/h2-5,7,9,15H,6,8,10H2,1H3;(H2,1,2,3,4)/t15-;/m0./s1
InChI key:InChIKey=FDEODCTUSIWGLK-RSAXXLAASA-N
SMILES:O=C(OC)C(C=1C=CC=CC1Cl)N2CC=3C=CSC3CC2.O=S(=O)(O)O
- Synonyms:
- (+)-(S)-5-[(2-Chlorophenyl)(methoxycarbonyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]-pyridin-5-ium hydrogen sulfate]
- (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid sulfate (1:1)
- (S)-(+)-Clopidogrel hydrogen sulfate
- (S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
- (S)-(+)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
- Areplex
- Clopidix
- Clopidogerl Bisulfate
- Clopidogrel Bisulfate
- Clopidogrel Bisulfate I
- See more synonyms
- Clopidogrel Bisulfate II
- Clopidogrel Bisulfate, FormI/FormII
- Clopidogrel Hydrogen Sulphate
- Clopidogrel Hydrogensulfate
- Clopidogrel Sulphate
- Clopidogrel bisulphate
- Clopidogrel bisulphate Ⅰ/Ⅱ
- Clopidogrel hemisulfate
- Clopidogrel sulfate
- Iscover
- Methyl (+)-(S)-A-(2-Chlorophenyl)-6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)Acetate, Hydrogen Sulfate Salt
- Methyl (S)-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)(2-chlorophenyl)ethanoate hydrogen sulfate
- Myogrel
- Plavitor
- Plavix
- Sr 25990C
- Stroka
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (S)-, sulfate (1:1)
- Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)
- Trombex
- Zyllt