CAS 120202-66-6

Clopidogrel hydrogen sulfate

Description:

Clopidogrel hydrogen sulfate is a pharmaceutical compound primarily used as an antiplatelet agent to prevent blood clots in patients at risk of cardiovascular events. It is a prodrug that requires metabolic activation in the liver to exert its therapeutic effects. The substance is characterized by its ability to irreversibly inhibit the P2Y12 receptor on platelets, thereby reducing platelet aggregation. Clopidogrel hydrogen sulfate is typically administered orally and is known for its relatively high bioavailability and long half-life, allowing for once-daily dosing. The compound is soluble in water and exhibits stability under normal storage conditions, although it should be protected from light and moisture. Common side effects may include bleeding complications, gastrointestinal disturbances, and hypersensitivity reactions. Due to its mechanism of action, it is often prescribed in conjunction with other antiplatelet or anticoagulant therapies, particularly in patients with a history of myocardial infarction or stroke. Monitoring for efficacy and adverse effects is essential during treatment.

Formula: C₁₅H₁₆ClNO₆S₂

InChI: InChI=1/C15H14ClNO2S.H2O4S/c16-12-4-2-1-3-11(12)14(15(18)19)17-7-5-13-10(9-17)6-8-20-13;1-5(2,3)4/h1-4,6,8,14H,5,7,9H2,(H,18,19);(H2,1,2,3,4)/t14-;/m0./s1

InChI key: InChIKey=FDEODCTUSIWGLK-RSAXXLAASA-N

SMILES: [C@H](C(OC)=O)(N1CC2=C(CC1)SC=C2)C3=C(Cl)C=CC=C3.S(=O)(=O)(O)O

Synonyms:

• (+)-(S)-5-[(2-Chlorophenyl)(methoxycarbonyl)methyl]-4,5,6,7-tetrahydrothieno[3,2-c]-pyridin-5-ium hydrogen sulfate]
• (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoic acid sulfate (1:1)
• (S)-(+)-Clopidogrel hydrogen sulfate
• (S)-(+)-Methyl (2-chlorophenyl)(6,7-dihydro-4H-thieno[3,2-c]pyrid-5-yl)acetate bisulfate
• (S)-(+)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate hydrogen sulfate
• Areplex
• Clopidix
• Clopidogerl Bisulfate
• Clopidogrel Bisulfate
• Clopidogrel Bisulfate I
• Clopidogrel Bisulfate II
• Clopidogrel Bisulfate, FormI/FormII
• Clopidogrel Hydrogen Sulphate
• Clopidogrel Hydrogensulfate
• Clopidogrel Sulphate
• Clopidogrel bisulphate
• Clopidogrel bisulphate Ⅰ/Ⅱ
• Clopidogrel hemisulfate
• Clopidogrel sulfate
• Iscover
• Methyl (+)-(S)-A-(2-Chlorophenyl)-6,7-Dihydrothieno[3,2-C]Pyridine-5(4H)Acetate, Hydrogen Sulfate Salt
• Methyl (S)-(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)(2-chlorophenyl)ethanoate hydrogen sulfate
• Myogrel
• Plavitor
• Plavix
• Sr 25990C
• Stroka
• Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (S)-, sulfate (1:1)
• Thieno[3,2-c]pyridine-5(4H)-acetic acid, α-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (αS)-, sulfate (1:1)
• Trombex
• Zyllt
• Clopidogrel hydrogen sulfate
• (S)-alpha-(2-Chlorophenyl)-6,7-dihydrothieno[3.2-c]pyridine-5(4H)-aceticacidmethylesterhydrogensulfate
• Clopidogrelhydrogenesulfate
• Clopidogrel (Hydrogen)
• (2-Chlorophenyl)-6,7–dihydrothieno[3,2-C]pyridine-5-(4H)-acetic acid methyl ester sulfate
• d-Clopidogrel

(S)-(+)-Clopidogrel Sulfate

CAS: 113665-84-2, 120202-66-6

Formula: C₁₆H₁₆ClNO₂S·H₂SO₄

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 419.89

Ref: 3B-C2556

Clopidogrel Hydrogen Sulphate

CAS: 120202-66-6

Color and Shape: Neat

Ref: 61-FOR0455.10

Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel hydrogen sulfate

Formula: C₁₆H₁₈ClNO₆S₂

Purity: 99.4%

Color and Shape: Off-White

Molecular weight: 419.02641

Ref: 47-1305

CLOPIDOGREL HYDROGEN SULFATE CRS

CAS: 120202-66-6

CLOPIDOGREL HYDROGEN SULFATE CRS

Formula: C₁₆H₁₈ClNO₆S₂

Color and Shape: White. Whitish. Powder.

Molecular weight: 419.9002

Ref: 41-Y0001333

CLOPIDOGREL FOR SYSTEM SUITABILITY CRS

CAS: 120202-66-6

CLOPIDOGREL FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0001334

Clopidogrel Bisulfate

CAS: 120202-66-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₆H₁₆ClNO₂S·H₂SO₄

Color and Shape: White Off-White Powder

Molecular weight: 321.05903

Ref: 45-1140430

Thieno[3,2-c]pyridine-5(4H)-acetic acid,a-(2-chlorophenyl)-6,7-dihydro-, methyl ester, (aS)-, sulfate (1:1)

CAS: 120202-66-6

Formula: C₁₆H₁₈ClNO₆S₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 419.9002

Ref: IN-DA00ILNY

Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel hydrogen sulfate is a selective P2Y12 receptor blocker that inhibits platelet adhesion and aggregation.

Formula: C₁₆H₁₆ClNO₂S·H₂SO₄

Purity: 99.57% - 99.79%

Color and Shape: Solid

Molecular weight: 419.9

Ref: TM-T0182L

Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel hydrogen sulfate

Purity: ≥98%

Molecular weight: 419.9g/mol

Ref: 54-BUP13803

Clopidogrel Sulfate

CAS: 120202-66-6

Formula: C₁₆H₁₆ClNO₂S·H₂SO₄

Color and Shape: White To Off-White Solid

Molecular weight: 321.82 98.07

Ref: 4Z-C-131

Clopidogrel Bisulfate

CAS: 120202-66-6

Clopidogrel Bisulfate

Purity: 99%

Molecular weight: 419.9g/mol

Ref: 54-OR1028933

Clopidogrel Hydrogen Sulphate

CAS: 120202-66-6

Color and Shape: Neat

Ref: 86-MM0455.10

(S)-(+)-Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Formula: C₁₆H₁₆ClNO₂S·H₂SO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 419.90

Ref: 7W-GK4784

Clopidogrel Sulfate RS

CAS: 120202-66-6

Color and Shape: White

Ref: 2K-1048900021

S-(+)-Clopidogrel Hydrogen Sulfate

CAS: 120202-66-6

Applications Used as an antithrombotic.
References Mills, D.C.B., et al.: Arterioscler. Thromb., 12, 430 (1992), Feuerstein, G., et al.: Exp. Opin. Invest. Drugs, 4, 425 (1995)

Formula: C₁₆H₁₆ClNO₂S·H₂O₄S

Color and Shape: Off-White

Molecular weight: 419.90

Ref: TR-C587250

S-(+)-Clopidogrel hydrogen sulfate

CAS: 120202-66-6

Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.

Formula: C₁₆H₁₈ClNO₆S₂

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 419.9 g/mol

Ref: 3D-FC20513

S-(+)-Clopidogrel hydrogen sulfate - Bio-X ™

CAS: 120202-66-6

Clopidogrel is a potent inhibitor of the platelet aggregation. It reduces blood clotting by inhibiting the ADP receptor on the surface of platelets, thereby inhibiting the aggregation and adhesion of platelets. Clopidogrel has been shown to be effective in preventing thrombosis, myocardial infarction (heart attack), and stroke. Clopidogrel inhibits the activity of cytochrome P450 3A4 (CYP3A4) and p2Y 12 receptors. Clopidogrel has been shown to have synergic effects with nonsteroidal anti-inflammatory drugs (NSAIDs). The polymorphic nature of Clopidogrel can be monitored using a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for quantification in biological samples such as human serum and plasma.

Formula: C₁₆H₁₆ClNO₂S•H₂SO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 419.9 g/mol

Ref: 3D-BC164326