CAS 1207-71-2

10H-Phenothiazine, 5-oxide

Description:

10H-Phenothiazine, 5-oxide, also known as phenothiazine oxide, is a heterocyclic compound characterized by its structure, which includes a phenothiazine backbone with an oxygen atom incorporated into the ring system. This compound typically appears as a solid and is known for its pale yellow to white color. It is soluble in organic solvents but has limited solubility in water. The presence of the oxygen atom in the phenothiazine structure alters its chemical reactivity and can influence its biological activity, making it of interest in various fields, including pharmaceuticals and materials science. Phenothiazine derivatives are often studied for their potential as antipsychotic agents and their role in photodynamic therapy due to their ability to generate reactive oxygen species upon light activation. Additionally, the compound may exhibit antioxidant properties and can be involved in redox reactions. Safety data indicates that it should be handled with care, as with many organic compounds, due to potential toxicity and environmental impact.

Formula: C₁₂H₉NOS

InChI: InChI=1S/C12H9NOS/c14-15-11-7-3-1-5-9(11)13-10-6-2-4-8-12(10)15/h1-8,13H

InChI key: InChIKey=DSAFSORWJPSMQS-UHFFFAOYSA-N

SMILES: O=S1C=2C(NC=3C1=CC=CC3)=CC=CC2

Synonyms:

• 10H-5λ4-Phenothiazin-5-one
• 10H-Phenothiazine, 5-oxide
• 5-Oxophenothiazine
• Akos 93707
• NSC 3554
• Phenothiazine S-oxide
• USAF do-16
• Phenothiazine, 5-oxide

Phenothiazine sulfoxide (5-Oxophenothiazine)

CAS: 1207-71-2

Compounds (excluding drugs) containing a phenothiazine ring-system (whether or not hydrogenated), not further fused

Formula: C₁₂H₉NOS

Color and Shape: Off-White Solid

Molecular weight: 215.04049

Ref: 45-1A06590

Sulfoxyde De Phenothiazine

CAS: 1207-71-2

Sulfoxyde De Phenothiazine

Formula: C₁₂H₉NOS

Purity: 97%

Color and Shape: Solid

Molecular weight: 215.27

Ref: 54-OR1025035

10H-Phenothiazine,5-oxide

CAS: 1207-71-2

Formula: C₁₂H₉NOS

Purity: 97%

Color and Shape: Solid

Molecular weight: 215.2710

Ref: IN-DA007PMZ

10H-Phenothiazine 5-oxide

CAS: 1207-71-2

10H-Phenothiazine 5-oxide

Formula: C₁₂H₉NOS

Purity: 95%

Molecular weight: 215.27

Ref: IN-DG427046

Phenothiazine Monoxide

CAS: 1207-71-2

Formula: C₁₂H₉NOS

Molecular weight: 215.27

Ref: 4Z-P-332002

10H-Phenothiazine 5-Oxide

CAS: 1207-71-2

Formula: C₁₂H₉NOS

Molecular weight: 215.27

Ref: ST-EA-CP-P86029

10H-Phenothiazine 5-Oxide

CAS: 1207-71-2

Applications 10H-Phenothiazine 5-Oxide is a by-product in the synthesis of Phenothiazine S,S-Dioxide (P297600). Phenothiazine S,S-Dioxide is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.
References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009); Baell, J., et al.: J. Med. Chem., 53, 2719 (2010); Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010); Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010); Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010)

Formula: C₁₂H₉NOS

Color and Shape: Neat

Molecular weight: 215.27

Ref: TR-P318098

10H-Phenothiazine 5-oxide

CAS: 1207-71-2

Purity: 98%

Molecular weight: 215.27000427246094

Ref: 10-F781022

Phenothiazine 5-oxide

CAS: 1207-71-2

Phenothiazine 5-oxide is a potent inhibitor of oxidative reactions that can be used to oxidize phenoxazine. Phenothiazine 5-oxide has been shown to inhibit the oxidation of phenoxazine by sodium hydroxide solution in an electrochemical study. This vibrational, irreversible oxidation reaction was introduced by the introduction of sodium salts, which are potent inhibitors of oxidative reactions. Phenothiazine 5-oxide has been shown to have potent inhibitory activity against cervical cancer cells and shows promise as a chemotherapeutic agent for this type of cancer.

Formula: C₁₂H₉NOS

Purity: Min. 95%

Molecular weight: 215.27 g/mol

Ref: 3D-BAA20771