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CAS 121-05-1

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N,N-Diisopropylethylenediamine

Description:
N,N-Diisopropylethylenediamine (DIPEA) is an organic compound characterized by its structure, which includes two isopropyl groups attached to a central ethylenediamine backbone. It is a colorless to pale yellow liquid with a strong amine odor. DIPEA is known for its role as a non-nucleophilic base in organic synthesis, particularly in reactions involving acylation and alkylation, where it helps to deprotonate substrates without participating in the reaction itself. The compound is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic isopropyl groups. DIPEA is also recognized for its relatively low toxicity, although it should be handled with care due to its irritating properties. Its boiling point is higher than that of many simple amines, reflecting its larger molecular size. Overall, N,N-Diisopropylethylenediamine is a valuable reagent in the field of organic chemistry, particularly in the synthesis of pharmaceuticals and other complex organic molecules.
Formula:C8H20N2
InChI:InChI=1S/C8H20N2/c1-7(2)10(6-5-9)8(3)4/h7-8H,5-6,9H2,1-4H3
InChI key:InChIKey=CURJNMSGPBXOGK-UHFFFAOYSA-N
SMILES:N(CCN)(C(C)C)C(C)C
Synonyms:
  • (2-Aminoethyl)bis(propan-2-yl)amine
  • 1,2-Ethanediamine, N,N-bis(1-methylethyl)-
  • 1,2-Ethanediamine, N<sup>1</sup>,N<sup>1</sup>-bis(1-methylethyl)-
  • 2-(Diisopropylamino)ethanamine
  • 2-Aminoethyldiisopropylamine
  • Ethylenediamine, N,N-diisopropyl-
  • N,N-Bis(1-methylethyl)-1,2-ethanediamine
  • N,N-Diisopropyl-1,2-ethanediamine
  • N,N-Diisopropylethylenediamine
  • N,N-Diisoprylamino Ethylamine
  • See more synonyms
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