CAS: 1211441-98-3 - LEE 011

Formula: C₂₃H₃0N₈O

InChI: InChI=1S/C23H30N8O/c1-29(2)22(32)19-13-16-14-26-23(28-21(16)31(19)17-5-3-4-6-17)27-20-8-7-18(15-25-20)30-11-9-24-10-12-30/h7-8,13-15,17,24H,3-6,9-12H2,1-2H3,(H,25,26,27,28)

InChI key: InChIKey=RHXHGRAEPCAFML-UHFFFAOYSA-N

SMILES: O=C(C1=CC=2C=NC(=NC2N1C3CCCC3)NC4=NC=C(C=C4)N5CCNCC5)N(C)C

Synonyms:

• 7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
• 7H-Pyrrolo[2,3-d]pyrimidine-6-carboxamide, 7-cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-
• Lee 011A
• Ribociclib

7-Cyclopentyl-N,N-dimethyl-2-[[5-(1-piperazinyl)-2-pyridinyl]amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide

CAS: 1211441-98-3

• Formula: C₂₃H₃₀N₈O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 434.5373

Ribociclib-d6

CAS: 1211441-98-31328934-40-2

• Formula: C₂₃H₂₄D₆N₈O
• Molecular weight: 440.58

Ribociclib

CAS: 1211441-98-3

• Formula: C₂₃H₃₀N₈O
• Molecular weight: 434.55

LEE011

CAS: 1211441-98-3

Ribociclib-d8

CAS: 1211441-98-3

• Formula: C₂₃H₂₂D₈N₈O
• Molecular weight: 442.60

Ribociclib

CAS: 1211441-98-3

Ribociclib (LEE011) is an orally available, and highly specific CDK4/6 inhibitor (IC50:10/39 nM).

• Formula: C₂₃H₃₀N₈O
• Purity: 100% - 99.96%
• Color and Shape: Solid
• Molecular weight: 434.54

LEE 011

CAS: 1211441-98-3

Applications LEE 011 can be used in biological study of kinome-wide RNA interference screen reveals …

• Formula: C₂₃H₃₀N₈O
• Color and Shape: Light Yellow To Beige
• Molecular weight: 434.54

Ribociclib

CAS: 1211441-98-3

Inhibitor of CDK4/6 serine/threonine kinases; antineoplastic

• Formula: C₂₃H₃₀N₈O
• Purity: Min. 95%
• Color and Shape: Powder
• Molecular weight: 434.54 g/mol