CAS 121268-17-5
:Alendronate monosodium trihydrate
Description:
Alendronate monosodium trihydrate is a bisphosphonate compound primarily used in the treatment of osteoporosis and other bone-related disorders. It functions by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density. This compound is characterized by its molecular formula, which includes sodium and water molecules, indicating its hydrated form. Alendronate monosodium trihydrate is typically a white to off-white crystalline powder, soluble in water but poorly soluble in organic solvents. Its stability is influenced by pH, with optimal activity observed in slightly acidic to neutral conditions. The compound is administered orally, and its pharmacokinetics involve significant absorption in the gastrointestinal tract, although it is subject to first-pass metabolism. Side effects may include gastrointestinal disturbances and potential renal implications, necessitating careful monitoring during treatment. Overall, Alendronate monosodium trihydrate plays a crucial role in managing conditions associated with bone density loss, contributing to improved patient outcomes in osteoporosis management.
Formula:C4H13NO7P2·3H2O·Na
InChI:InChI=1S/C4H13NO7P2.Na.3H2O/c5-3-1-2-4(6,13(7,8)9)14(10,11)12;;;;/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12);;3*1H2
InChI key:InChIKey=PXPDLXULFWKPSB-UHFFFAOYSA-N
SMILES:C(P(=O)(O)O)(P(=O)(O)O)(CCCN)O.[Na].O
Synonyms:- (4-Amino-1-Hydroxybutane-1,1-Diyl)Bis(Phosphonic Acid)
- (4-Ammonio-1-Hydroxybutane-1,1-Diyl)Bis[Hydrogen (Phosphonate)]
- 4-Amino-1-Hydroxybutylidene-1,1-Bisphosphonic Acid Monosodium Salt Trihydrate
- Alendronate monosodium trihydrate
- Alendronate sodium hydrate
- Alendronic Acid Monosodium Salt Trihydrate
- Alendros Trihydrate
- Bifosa Trihydrate
- Fosalan Trihydrate
- Fosamaxtrihydrate
- Mandeloeltrihydrate
- Monosodium Alendronatetrihydrate
- Monosodium alendronate trihydrate
- Neobon Trihydrate
- Osteovan Trihydrate
- Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-, monosodium salt, trihydrate
- Phosphonic acid, P,P′-(4-amino-1-hydroxybutylidene)bis-, sodium salt, hydrate (1:1:3)
- Sodium Hydrogen (4-Amino-1-Hydroxy-1-Phosphonobutyl)Phosphonate
- Sodium Hydrogen (4-Amino-1-Hydroxy-1-Phosphonobutyl)Phosphonate Hydrate (1:1:3)
- Sodium alendronate hydrate
- Teiroc
- See more synonyms
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Found 18 products.
Alendronic Acid
CAS:Formula:C4H13NO7P2Purity:>98.0%(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:249.10Alendronate sodium trihydrate, 97%
CAS:<p>Alendronate sodium trihydrate is used as a bone resorption inhibitor, farnesyl diphosphate synthase inhibitor and CD45 protein tyrosine phosphatase inhibitor. A robust inhibitor of bone resorption that induces apoptosis. Alendronate inhibits the migration and invasion of PC-3 cells (sc-2220) by inte</p>Formula:C4H18NNaO10P2Purity:97%Color and Shape:Powder or crystals or crystalline powder, White to pale creamMolecular weight:325.12SODIUM ALENDRONATE TRIHYDRATE CRS
CAS:<p>SODIUM ALENDRONATE TRIHYDRATE CRS</p>Formula:C4H18NNaO10P2Color and Shape:Added ModifiedMolecular weight:325.1237SODIUM ALENDRONATE FOR SYSTEM SUITABILITY CRS
CAS:<p>SODIUM ALENDRONATE FOR SYSTEM SUITABILITY CRS</p>Sodium alendronate
CAS:Sodium alendronateFormula:C4H12NNAO7P2Purity:83.5%Color and Shape:WhiteMolecular weight:325.1237Alendronate Sodium
CAS:Non-halogenated organo-phosphorous derivatives, nesoiFormula:C4H12NNaO7P2·3H2OColor and Shape:White PowderMolecular weight:325.03036Phosphonic acid, (4-amino-1-hydroxybutylidene)bis-, monosodium salt, trihydrate
CAS:Formula:C4H18NNaO10P2Purity:97%Color and Shape:SolidMolecular weight:325.1237Alendronate Sodium Trihydrate
CAS:<p>Alendronate Sodium Trihydrate</p>Purity:98%Molecular weight:325.12g/molAlendronate sodium salt trihydrate
CAS:Formula:C4H12NaNO7P2·3H2OPurity:≥ 99.0% (dried basis)Color and Shape:White powderMolecular weight:325.12Sodium Alendronate
CAS:Controlled ProductFormula:C4H12NO7P2·NaH2OColor and Shape:WhiteMolecular weight:325.12Alendronate monosodium trihydrate
CAS:Purity:95.0%Color and Shape:Solid, White - Almost white powderMolecular weight:325.12200927734375Alendronate Sodium Trihydrate
CAS:Formula:C4H12NNaO7P2·3H2OPurity:>97.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:325.13Alendronate sodium trihydrate
CAS:<p>Alendronate sodium hydrate (MK 217), a nitrogen bisphosphonate, inhibits bone loss, treats and prevents osteoporosis.</p>Formula:C4H12NO7P2·3H2O·NaPurity:99.66% - 99.90%Color and Shape:White Crystalline SolidMolecular weight:325.12Alendronic Acid Monosodium Salt Trihydrate
CAS:Controlled Product<p>Stability Store in freezer<br>Applications A bisphosphonate used as a bone reabsoption inhibitor.<br>References Wang, X.M., et al.: Clin. J. Dent. Res., 3, 26 (2000), Woo, T., et al.: Best Pract. Res. Clin. Rheumatol., 15, 469 (2001), Benford, H.L., et al.: Bone, 28, 465 (2001),<br></p>Formula:C4H12NO7P2·Na·3H2OColor and Shape:WhiteMolecular weight:325.12Alendronic acid monosodium salt trihydrate - USP
CAS:<p>Farnesyl diphosphate synthase inhibitor; inhibits bone resorption</p>Formula:C4H18NNaO10P2Purity:Min. 95%Color and Shape:White PowderMolecular weight:325.12 g/molAlendronic acid monosodium salt trihydrate
CAS:<p>Farnesyl diphosphate synthase inhibitor; inhibits bone resorption</p>Formula:C4H18NNaO10P2Purity:Min. 95%Molecular weight:325.12 g/mol
