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CAS 66376-36-1

:

Alendronic acid

Description:
Alendronic acid, with the CAS number 66376-36-1, is a bisphosphonate compound primarily used in the treatment of osteoporosis and other bone-related disorders. It functions by inhibiting osteoclast-mediated bone resorption, thereby increasing bone mineral density and reducing the risk of fractures. Alendronic acid is characterized by its ability to bind to hydroxyapatite in bone, which enhances its therapeutic efficacy. The compound is typically administered orally and is known for its relatively low bioavailability, necessitating specific dosing instructions, such as taking it on an empty stomach with a full glass of water and remaining upright for a period afterward to minimize gastrointestinal irritation. Alendronic acid is generally well-tolerated, but potential side effects may include gastrointestinal discomfort, musculoskeletal pain, and, in rare cases, osteonecrosis of the jaw. Its chemical structure includes a phosphonate group, which is crucial for its biological activity, and it is classified as a synthetic organic compound.
Formula:C4H13NO7P2
InChI:InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12)
InChI key:InChIKey=OGSPWJRAVKPPFI-UHFFFAOYSA-N
SMILES:C(P(=O)(O)O)(P(=O)(O)O)(CCCN)O
Synonyms:
  • (4-Amino-1-hydroxy-1-phosphonobutyl) phosphonic acid
  • (4-Amino-1-hydroxybutylidene)bisphosphonic acid
  • 4-Amino-1-hydroxybutane-1,1-bisphosphonic acid
  • 4-Amino-1-hydroxybutane-1,1-diphosphonate
  • 4-Amino-1-hydroxybutane-1,1-diphosphonic acid
  • 4-Amino-1-hydroxybutane-1,1-diyldiphosphonic acid
  • 4-Amino-1-hydroxybutylidene-1,1-bis(phosphonic acid)
  • A-Hydroxy-D-Aminobutylidenediphosphonic Acid
  • Abdp
  • Bph 1
  • See more synonyms
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