CAS 121288-39-9

Loxoribine

Description:

Loxoribine is a synthetic nucleoside analog that exhibits immunomodulatory properties, primarily functioning as an agonist of Toll-like receptor 7 (TLR7). This compound is characterized by its ability to stimulate the immune response, making it of interest in the context of antiviral and anticancer therapies. Loxoribine is typically administered in a pharmaceutical form and is known for its potential to enhance the activity of immune cells, such as macrophages and dendritic cells. The chemical structure of Loxoribine includes a ribose sugar moiety, which is essential for its biological activity, and it is often studied for its effects on cytokine production and T-cell activation. Its CAS number, 121288-39-9, is a unique identifier that facilitates the tracking and study of this compound in scientific literature and databases. Overall, Loxoribine represents a significant area of research in immunotherapy, with ongoing studies exploring its efficacy and mechanisms of action in various disease models.

Formula: C₁₃H₁₇N₅O₆

InChI: InChI=1S/C13H17N5O6/c1-2-3-17-6-9(15-12(14)16-10(6)22)18(13(17)23)11-8(21)7(20)5(4-19)24-11/h2,5,7-8,11,19-21H,1,3-4H2,(H3,14,15,16,22)/t5-,7-,8-,11-/m1/s1

InChI key: InChIKey=VDCRFBBZFHHYGT-IOSLPCCCSA-N

SMILES: O=C1N(C2=C(N1CC=C)C(=O)N=C(N)N2)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O

Synonyms:

• 7,8-Dihydro-8-oxo-7-(2-propen-1-yl)guanosine
• 7-Allyl-2-amino-9-beta-D-ribofuranosylpurine-6,8(1H,9H)-dione
• 7-Allyl-8-oxoguanosine
• 8-Oxo-7-Prop-2-En-1-Ylguanosine
• Guanosine, 7,8-dihydro-8-oxo-7-(2-propen-1-yl)-
• Guanosine, 7,8-dihydro-8-oxo-7-(2-propenyl)-
• Loxoribina
• Loxoribina [INN-Spanish]
• Loxoribine [USAN:INN]
• Loxoribinum
• Loxoribinum [INN-Latin]
• Rwj 21757
• Unii-9Cas0V66Oi

7-ALLYL-7 8-DIHYDRO-8-OXOGUANOSINE 95

CAS: 121288-39-9

Formula: C₁₃H₁₇N₅O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 339.3040

Ref: IN-DA009ELU

Loxoribine

CAS: 121288-39-9

Loxoribine (RWJ 21757), a guanosine analog, is an oral TLR7 agonist with antiviral and antitumor properties.

Formula: C₁₃H₁₇N₅O₆

Purity: 99.11%

Color and Shape: Solid

Molecular weight: 339.3

Ref: TM-T15777

Loxoribine

CAS: 121288-39-9

Loxoribine

Formula: C₁₃H₁₇N₅O₆

Purity: ≥98%

Molecular weight: 339.3

Ref: 54-BUP10343

Loxoribine

CAS: 121288-39-9

Loxoribine

Formula: C₁₃H₁₇N₅O₆

Purity: ≥98%

Molecular weight: 339.31

Ref: 54-OR1024389

7-Allyl-7,8-dihydro-8-oxoguanosine

CAS: 121288-39-9

Formula: C₁₃H₁₇N₅O₆

Purity: ≥ 95.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 339.3

Ref: 7W-GN8466

7-Allyl-7,8-dihydro-8-oxoguanosine

CAS: 121288-39-9

Agonist of toll-like receptors TLR7

Formula: C₁₃H₁₇N₅O₆

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 339.3 g/mol

Ref: 3D-NA07175

7-Allyl-7,8-dihydro-8-oxoguanosine(Loxoribine)

Controlled Product

CAS: 121288-39-9

Formula: C₁₃H₁₇N₅O₆

Color and Shape: Neat

Molecular weight: 339.3

Ref: TR-A550000