CAS 1215667-16-5

N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester 1,4- Dioxane complex

Controlled Product

CAS: 1215667-16-5

Applications A short, amino reactive homobifunctional crosslinking reagent. Crosslinking distance 8.3 Å. It is useful in polymer coupling to proteins, because it may lead to a better selectivity among all the amino groups present in a protein, thus yielding less heterogeneous PEG-protein conjugates mixture because only the most nucleophilic and solvent exposed amines can react.
References Gross, H., et al.: Tetrahedron, 24, 6935 (1968), Clark, R., et al.: J. Biol. Chem., 271, 21969 (1996), Guiotto, A., et al.: Bioorg. Med. Chem., 12, 5031 (2004),

Formula: C₁₂H₁₃N₃O₈·C₄H₈O₂

Color and Shape: Neat

Molecular weight: 415.35

Ref: TR-S689850