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CAS 122-80-5

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N-(4-Aminophenyl)acetamide

Description:
N-(4-Aminophenyl)acetamide, also known as para-aminophenylacetamide, is an organic compound characterized by its amide functional group attached to a para-aminophenyl moiety. It typically appears as a white to off-white crystalline solid and is soluble in polar solvents such as water and alcohols. This compound is known for its role in various chemical syntheses and as an intermediate in the production of pharmaceuticals, particularly analgesics and antipyretics. Its molecular structure features an acetamide group (-C(=O)NH2) linked to a para-aminophenyl group, which contributes to its biological activity. The compound exhibits properties such as moderate melting and boiling points, and it may undergo typical reactions associated with amides, including hydrolysis and acylation. Safety data indicates that it should be handled with care, as it may pose health risks upon exposure. Overall, N-(4-Aminophenyl)acetamide is significant in both industrial applications and research contexts, particularly in medicinal chemistry.
Formula:C8H10N2O
InChI:InChI=1/C8H10N2O/c1-6(11)10-8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11)
InChI key:InChIKey=CHMBIJAOCISYEW-UHFFFAOYSA-N
SMILES:N(C(C)=O)C1=CC=C(N)C=C1
Synonyms:
  • (4-(Acetylamino)phenyl)amine
  • 1-Amino-4-(acetylamino)benzene
  • 4'-Aminoacetanilid
  • 4'-Aminoacetanilida
  • 4'-Aminoacetanilide
  • 4-(Acetylamino)aniline
  • 4-Acetamidoaniline
  • 4-Acetoamidoaniline
  • 4-Acetylaminobenzeneamine
  • 4-Amino-N-acetylaniline
  • See more synonyms
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