CAS 1221971-47-6

PF-9184

Description:

PF-9184, identified by its CAS number 1221971-47-6, is a chemical compound that belongs to a class of substances known for their potential applications in various fields, including pharmaceuticals and materials science. While specific characteristics such as molecular structure, physical properties, and reactivity may vary, compounds like PF-9184 are typically evaluated for their biological activity, stability, and solubility. In the context of drug development, such substances are often studied for their efficacy against specific targets, safety profiles, and pharmacokinetic properties. Additionally, the compound may exhibit unique interactions with biological systems, making it of interest for further research. As with any chemical, handling and usage should adhere to safety guidelines to mitigate risks associated with exposure. For detailed information, including synthesis methods and specific applications, consulting scientific literature or databases is recommended.

Formula: C₂₁H₁₄Cl₂N₂O₄S

InChI: InChI=1S/C21H14Cl2N2O4S/c22-16-10-7-13(11-17(16)23)12-5-8-14(9-6-12)24-21(27)19-20(26)15-3-1-2-4-18(15)30(28,29)25-19/h1-11,25-26H,(H,24,27)

InChI key: VGACSWBJQLLJFB-UHFFFAOYSA-N

SMILES: C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)C4=CC(=C(C=C4)Cl)Cl)O

Synonyms:

• 2H-1,2-Benzothiazine-3-carboxamide, N-(3',4'-dichloro[1,1'-biphenyl]-4-yl)-4-hydroxy-, 1,1-dioxide
• PF-9184
• N-[3',4'-Dichloro(1,1'-biphenyl)-yl]-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide
• PF-03549184

PF-9184

CAS: 1221971-47-6

PF-9184

Formula: C₂₁H₁₄Cl₂N₂O₄S

Purity: 97%

Molecular weight: 461.32

Ref: 54-BUP16292

PF-9184

CAS: 1221971-47-6

PF-9184 inhibits human mPGES-1 selectively, with an IC50 of 16.5 nM, and reduces IL-1β-stimulated PGE2 production in vitro.

Formula: C₂₁H₁₄Cl₂N₂O₄S

Purity: 97.43%

Color and Shape: Solid

Molecular weight: 461.318

Ref: TM-T21738

PF-9184

CAS: 1221971-47-6

Ref: IN-DA00A18T

PF-03549184

CAS: 1221971-47-6

PF-03549184 is a novel pharmacological compound, classified as a selective GABA_A receptor modulator. It is synthetically derived through advanced chemical processes to achieve high specificity and potency. The mode of action of PF-03549184 involves targeting specific subtypes of the GABA_A receptor, which plays a significant role in inhibitory neurotransmission in the central nervous system. By modulating these receptors, PF-03549184 enhances synaptic transmission and neural network function.

Formula: C₂₁H₁₄Cl₂N₂O₄S

Purity: Min. 95%

Molecular weight: 461.32 g/mol

Ref: 3D-WYB97147

N-(3,4-Dichloro[1,1-biphenyl]-4-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

CAS: 1221971-47-6

Formula: C₂₁H₁₄Cl₂N₂O₄S

Molecular weight: 461.31

Ref: ST-EA-CP-A124014