CAS 1224844-38-5

3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Description:

3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a chemical compound characterized by its complex structure, which includes a pyrazolo[3,4-d]pyrimidine core fused with a benzoxazole moiety. This compound features multiple functional groups, including an amino group and an isopropyl substituent, which contribute to its potential biological activity. The presence of the benzoxazole ring suggests possible interactions with biological targets, making it of interest in medicinal chemistry. The compound's molecular structure may exhibit properties such as solubility in organic solvents and potential for hydrogen bonding due to the amino groups. Its CAS number, 1224844-38-5, allows for easy identification in chemical databases. While specific physical properties like melting point, boiling point, and solubility are not provided, compounds of this nature often exhibit varied pharmacological activities, which could include anti-inflammatory or anticancer effects, warranting further investigation in drug development contexts.

Formula: C₁₅H₁₅N₇O

InChI: InChI=1S/C15H15N7O/c1-7(2)22-14-11(13(16)18-6-19-14)12(21-22)8-3-4-10-9(5-8)20-15(17)23-10/h3-7H,1-2H3,(H2,17,20)(H2,16,18,19)

InChI key: InChIKey=GYLDXIAOMVERTK-UHFFFAOYSA-N

SMILES: NC1=C2C(=NN(C(C)C)C2=NC=N1)C=3C=C4C(=CC3)OC(N)=N4

Synonyms:

• Sapanisertib
• 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
• MLN 0128
• 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(2-amino-5-benzoxazolyl)-1-(1-methylethyl)-
• INK 128

1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(2-amino-5-benzoxazolyl)-1-(1-methylethyl)-

CAS: 1224844-38-5

Formula: C₁₅H₁₅N₇O

Purity: 99%

Color and Shape: Solid

Molecular weight: 309.3259

Ref: IN-DA0017AM

Sapanisertib

CAS: 1224844-38-5

Sapanisertib

Purity: ≥98%

Molecular weight: 309.33g/mol

Ref: 54-BUP15073

5-(4-Amino-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Benzo[D]Oxazol-2-Amine

CAS: 1224844-38-5

5-(4-Amino-1-Isopropyl-1H-Pyrazolo[3,4-D]Pyrimidin-3-Yl)Benzo[D]Oxazol-2-Amine

Purity: 99%

Molecular weight: 309.33g/mol

Ref: 54-OR1025699

Sapanisertib

CAS: 1224844-38-5

Sapanisertib (INK 128) is an oral raptor-mTOR and rictor-mTOR inhibitor with potential cancer-fighting properties.

Formula: C₁₅H₁₅N₇O

Purity: 99.19% - >99.99%

Color and Shape: Solid

Molecular weight: 309.33

Ref: TM-T1838

MLN0128

CAS: 1224844-38-5

Ref: 7W-GW9035

3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Controlled Product

CAS: 1224844-38-5

Stability Hygroscopic
Applications 3-(2-Amino-5-benzoxazolyl)-1-(1-methylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is a potent and selective TORC1/2 inhibitor with broad oral antitumor activity. TORC1/2 inhibitors are mechanistically distinct from rapamycinand offer a compelling approach to the treatment of cancer by targeting translational control, cell metabolism, growth andangiogenesis.
References Katayoun, J., et al.: Molec. Cancer. Therap., 8, 1158 (2009);

Formula: C₁₅H₁₅N₇O

Color and Shape: Neat

Molecular weight: 309.33

Ref: TR-A602050

Sapanisertib

CAS: 1224844-38-5

ATP-dependent inhibitor of mTOR1/2

Formula: C₁₅H₁₅N₇O

Purity: Min. 95%

Molecular weight: 309.33 g/mol

Ref: 3D-BS170924