CAS 1227911-45-6

GSK2334470

Description:

GSK2334470, with the CAS number 1227911-45-6, is a chemical compound that has been investigated primarily for its potential therapeutic applications. It is classified as a small molecule and is known to act as a selective inhibitor of certain protein kinases, which play crucial roles in various cellular processes, including cell growth, differentiation, and metabolism. The compound's mechanism of action typically involves the modulation of signaling pathways associated with diseases such as cancer and inflammatory disorders. In terms of its physical and chemical properties, GSK2334470 may exhibit characteristics common to small organic molecules, such as moderate solubility in organic solvents and specific stability under standard laboratory conditions. Its development has been part of research efforts aimed at discovering new treatments, and ongoing studies may further elucidate its efficacy and safety profiles. As with any investigational compound, detailed pharmacokinetic and toxicological studies are essential to understand its potential as a therapeutic agent.

GSK 2334470

CAS: 1227911-45-6

Formula: C₂₅H₃₄N₈O

Purity: 99%

Color and Shape: Solid

Molecular weight: 462.5905

Ref: IN-DA009CC0

GSK2334470

CAS: 1227911-45-6

GSK2334470

Purity: ≥98%

Molecular weight: 462.59g/mol

Ref: 54-BUP14267

GSK2334470

CAS: 1227911-45-6

Formula: C₂₅H₃₄N₈O

Purity: ≥ 98.0%

Color and Shape: Beige to light brown powder

Molecular weight: 462.59

Ref: 7W-GK2665

GSK2334470

CAS: 1227911-45-6

GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.

Formula: C₂₅H₃₄N₈O

Purity: 99.57% - 99.87%

Color and Shape: Solid

Molecular weight: 462.59

Ref: TM-T2348

GSK 2334470

CAS: 1227911-45-6

GSK 2334470 is a small molecule that inhibits the activity of the protein kinase CDK4/6. It is a potent inhibitor of tnf-related apoptosis-inducing ligand (TRAIL)-induced cell death and targets amyloid precursor proteins. GSK 2334470 has been shown to suppress the growth of hematopoietic cells in vitro, which may be due to its ability to inhibit cdk4/6 activity. In addition, GSK 2334470 selectively inhibits the kinase activity of CDK4/6 and has no effect on other kinases such as PDK1, cyclin B1, or MAP2K2.

Formula: C₂₅H₃₄N₈O

Purity: Min. 95%

Molecular weight: 462.59 g/mol

Ref: 3D-FG172878