CAS 1229-29-4
:Doxepin hydrochloride
Description:
Doxepin hydrochloride is a tricyclic antidepressant primarily used to treat depression and anxiety disorders, as well as insomnia. It functions by inhibiting the reuptake of neurotransmitters such as norepinephrine and serotonin, thereby enhancing mood and promoting sleep. This compound appears as a white to off-white crystalline powder and is soluble in water, making it suitable for various pharmaceutical formulations. Doxepin hydrochloride exhibits a relatively long half-life, allowing for once-daily dosing in many cases. Its pharmacological effects can include sedation, which is beneficial for patients with sleep disturbances. However, it may also lead to side effects such as dry mouth, dizziness, and weight gain. Due to its anticholinergic properties, caution is advised in patients with certain pre-existing conditions, such as glaucoma or urinary retention. Overall, doxepin hydrochloride is a versatile medication with a well-established profile in the management of mood and sleep disorders.
Formula:C19H21NO·ClH
InChI:InChI=1S/C19H21NO.ClH/c1-20(2)13-7-11-17-16-9-4-3-8-15(16)14-21-19-12-6-5-10-18(17)19;/h3-6,8-12H,7,13-14H2,1-2H3;1H
InChI key:InChIKey=MHNSPTUQQIYJOT-UHFFFAOYSA-N
SMILES:C(CCN(C)C)=C1C=2C(COC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:- (3E)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
- (3Z)-3-dibenzo[b,e]oxepin-11(6H)-ylidene-N,N-dimethylpropan-1-amine hydrochloride
- 1-Propanamine, 3-(dibenz[b,e]oxepin-11(6H)-ylidene)-N,N-dimethyl-, hydrochloride (1:1)
- 1-Propanamine, 3-dibenz[b,e]oxepin-11(6H)-ylidene-N,N-dimethyl-, hydrochloride
- 11-(3-Dimethylaminopropylidene)-6,11-Dihydro-Benz[B,E]Oxepin Hcl
- 3-(6,11-Dihydrodibenz(B,E)Oxepin-11-Ylidene)Propyldimethylamine Hcl
- 3-(dibenzo[b,e]oxepin-11(6H)-ylidene)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
- Adapin
- Aponal
- Curatin
- Dibenz[b,e]oxepin, 1-propanamine deriv.
- Dibenz[b,e]oxepin-Δ<sup>11(6</sup><sup>H</sup><sup>),γ</sup>-propylamine, N,N-dimethyl-, hydrochloride
- Doxepin Hydrochloride
- Doxepine hydrochloride
- N,N-Dimethyldibenz[b,e]oxepin-Δ<sup>11(6</sup><sup>H</sup><sup>),γ</sup>-propylamine hydrochloride
- P 3693A
- Quitaxon
- Silenor
- Sinequan
- Sinequin
- DOXEPINONE HCl
- See more synonyms
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Found 24 products.
Doxepin Hydrochloride (mixture of isomers)
CAS:Formula:C19H21NO·HClPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:315.84Doxepin hydrochloride
CAS:<p>Potent H1-histamine receptor antagonist and a 5-HT receptor antagonist</p>Formula:C19H22ClNOMolecular weight:315.84DOXEPIN FOR SYSTEM SUITABILITY CRS
CAS:<p>DOXEPIN FOR SYSTEM SUITABILITY CRS</p>Formula:C19H22ClNOColor and Shape:Crystalline Powder. White. Whitish. Powder.Molecular weight:315.8371Doxepin hydrochloride
CAS:Doxepin hydrochlorideFormula:C19H21NOHClPurity:99.5% / 21.7%Color and Shape:WhiteDOXEPIN HYDROCHLORIDE CRS
CAS:<p>DOXEPIN HYDROCHLORIDE CRS</p>Formula:C19H22ClNOColor and Shape:Crystalline Powder. White. Whitish. Powder.Molecular weight:315.8371Doxepin Hydrochloride
CAS:Aromatic heterocyclic compounds with oxygen hetero-atom(s) only, nesoiFormula:C19H21NO·ClHColor and Shape:White PowderMolecular weight:315.13899Doxepin hydrochloride
CAS:<p>Doxepin hydrochloride, a dibenzoxepin tricyclic, blocks monoamine reuptake and has anticholinergic and antihistaminic effects. Mechanism partly unknown.</p>Formula:C19H22ClNOPurity:99.65% - 99.91%Color and Shape:White To Off-White PowderMolecular weight:315.84dimethyl({3-[(2E)-9-oxatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene]propyl})amine hydrochloride
CAS:Formula:C19H22ClNOPurity:98%Color and Shape:SolidMolecular weight:315.8371Doxepin HCl (Mixture of Z and E Isomer)
CAS:Formula:C19H21NO·HClColor and Shape:White To Off-White SolidMolecular weight:279.39 36.46Doxepin hydrochloride
CAS:Controlled ProductFormula:C19H21NO·ClHColor and Shape:NeatMolecular weight:315.84Doxepin Hydrochloride
CAS:Controlled Product<p>Stability Hygroscopic<br>Applications Doxepin is used clinically to treat anxiety and depression. Doxepin is an antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ribbentrop, A., et al.: Arzneim.-Forsch., 15, 863 (1965); Hobbs, D.C., et al.: Biochem. Pharmacol., 18, 1941 (1969); Pinder, R.M., et al.: Drugs, 13, 161 (1977); Shrivastava, R.K., et al.: Clin. Ther., 7, 181 (1985);<br></p>Formula:C19H21NO·ClHColor and Shape:NeatMolecular weight:315.84Doxepin-13C, d3 .xHydrochloride
CAS:Controlled ProductFormula:C18CH18D3NO•x(HCl)Color and Shape:NeatMolecular weight:318.15782Doxepin hydrochloride
CAS:Controlled Product<p>Histamine receptor H1 antagonist; tricyclic antidepressant</p>Formula:C19H22ClNOPurity:Min. 95%Color and Shape:PowderMolecular weight:315.84 g/molDoxepin HCl - Bio-X ™
CAS:Controlled Product<p>Doxepin is a psychotropic agent that is used in the treatment of depression, anxiety and insomnia. This drug has antidepressant and anxiolytic properties. This mechanism of action for this drug is not clear however it is known to be a histamine receptor antagonist.</p>Formula:C19H21NO•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:315.84 g/mol
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